Literature DB >> 25888569

Is nitric oxide really the primary mediator of pancreatic β-cell death in type 1 diabetes?

Ewa Gurgul-Convey1, Sigurd Lenzen1.   

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Year:  2015        PMID： 25888569      PMCID： PMC4400364          DOI： 10.1074/jbc.L115.648089

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  5 in total

1.  Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria.

Authors:  Ewa Gurgul-Convey; Ilir Mehmeti; Stephan Lortz; Sigurd Lenzen
Journal:  J Mol Med (Berl)       Date:  2011-04-13       Impact factor: 4.599

2.  Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetes.

Authors:  Anne Jörns; Tanja Arndt; Andreas Meyer zu Vilsendorf; Jürgen Klempnauer; Dirk Wedekind; Hans-Jürgen Hedrich; Lorella Marselli; Piero Marchetti; Nagakatsu Harada; Yutaka Nakaya; Gen-Sheng Wang; Fraser W Scott; Conny Gysemans; Chantal Mathieu; Sigurd Lenzen
Journal:  Diabetologia       Date:  2013-12-06       Impact factor: 10.122

3.  How the location of superoxide generation influences the β-cell response to nitric oxide.

Authors:  Katarzyna A Broniowska; Bryndon J Oleson; Jennifer McGraw; Aaron Naatz; Clayton E Mathews; John A Corbett
Journal:  J Biol Chem       Date:  2015-02-03       Impact factor: 5.157

4.  Impaired glucose-stimulated insulin secretion is coupled with exocrine pancreatic lesions in the Cohen diabetic rat.

Authors:  Sarah Weksler-Zangen; Itamar Raz; Sigurd Lenzen; Anne Jörns; Shira Ehrenfeld; Gail Amir; Andrei Oprescu; Yoram Yagil; Chana Yagil; David H Zangen; Nurit Kaiser
Journal:  Diabetes       Date:  2007-10-31       Impact factor: 9.461

Review 5.  Oxidative stress: the vulnerable beta-cell.

Authors:  Sigurd Lenzen
Journal:  Biochem Soc Trans       Date:  2008-06       Impact factor: 5.407
  5 in total
  2 in total

1.  Reply to Gurgul-Convey and Lenzen: Cytokines, nitric oxide, and β-cells.

Authors:  Katarzyna A Broniowska; Clayton E Mathews; John A Corbett
Journal:  J Biol Chem       Date:  2015-04-17       Impact factor: 5.157

2.  Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated.

Authors:  Shiva Reddy; Lars Krogvold; Charlton Martin; Kevin Xueying Sun; Owen Martin; Aamenah Al-Ani; Knut Dahl-Jørgensen
Journal:  Cell Tissue Res       Date:  2021-01-11       Impact factor: 5.249
  2 in total

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