Sung Ho Jang1, Jeong Pyo Seo. 1. Department of Physical Medicine and Rehabilitation (SHJ, JPS), College of Medicine, Yeungnam University, Daemyungdong, Namku, Taegu, Republic of Korea.
Abstract
BACKGROUND: There are known limitations of conventional computed tomography and magnetic resonance imaging in detecting neural injury in patients with mild traumatic brain injury (TBI). Diffusion tensor imaging (DTI) provides a method to further assess cerebral injury in this patient population. We report 2 patients with mild TBI who showed injury of the optic radiation (OR) as demonstrated by DTI. METHOD: Two patients who complained of visual field loss after mild TBI and 9 age-matched normal control subjects were recruited for this study. Peripheral field defects were detected with automated perimetry in both patients. RESULTS: Regarding the configuration of OR, the total volume of OR was decreased in the right OR of both patients compared with controls; in contrast, the left ORs were divided into 2 parts in both patients. The voxel numbers of both ORs in both patients were more than 2 standard deviations lower than that of normal control subjects. The apparent diffusion coefficient value of the right OR in patient 2 was more than 2 standard deviations higher than that of normal controls. CONCLUSIONS: We demonstrated injury of the OR using DTI in 2 patients who showed visual field defects after mild TBI.
BACKGROUND: There are known limitations of conventional computed tomography and magnetic resonance imaging in detecting neural injury in patients with mild traumatic brain injury (TBI). Diffusion tensor imaging (DTI) provides a method to further assess cerebral injury in this patient population. We report 2 patients with mild TBI who showed injury of the optic radiation (OR) as demonstrated by DTI. METHOD: Two patients who complained of visual field loss after mild TBI and 9 age-matched normal control subjects were recruited for this study. Peripheral field defects were detected with automated perimetry in both patients. RESULTS: Regarding the configuration of OR, the total volume of OR was decreased in the right OR of both patients compared with controls; in contrast, the left ORs were divided into 2 parts in both patients. The voxel numbers of both ORs in both patients were more than 2 standard deviations lower than that of normal control subjects. The apparent diffusion coefficient value of the right OR in patient 2 was more than 2 standard deviations higher than that of normal controls. CONCLUSIONS: We demonstrated injury of the OR using DTI in 2 patients who showed visual field defects after mild TBI.
Authors: Thomas Decramer; Karel Van Keer; Peter Stalmans; Patrick Dupont; Stefan Sunaert; Tom Theys Journal: J Neurol Date: 2017-11-06 Impact factor: 4.849