AIM: To develop evidence-based recommendations for the diagnosis and management of gout in Australia and New Zealand as part of the multi-national 3e Initiative. METHOD: Using a formal voting process, a panel of 78 international rheumatologists selected 10 key clinical questions pertinent to the diagnosis and management of gout. An additional question was also developed by participating Australian and New Zealand rheumatologists. Each question was investigated with a systematic literature review. MEDLINE, EMBASE, Cochrane CENTRAL and abstracts from 2010 to 2011 European League Against Rheumatism and American College of Rheumatology meetings were searched in each review. Relevant studies were independently reviewed by two individuals for data extraction and synthesis and risk of bias assessment. Using this evidence, 47 Australian and New Zealand rheumatologists developed national recommendations. For each recommendation the level of agreement was assessed and the level of evidence graded. RESULT: Eleven recommendations were produced relating to the diagnosis of gout, different aspects of the management of gout, cardiovascular and renal comorbidities and the management of asymptomatic hyperuricemia. The mean level of agreement with the recommendations was 9.1 on a 1-10 scale, with 10 representing full agreement. CONCLUSION: Eleven Australian and New Zealand recommendations on the diagnosis and management of gout were developed combining systematically reviewed evidence with local expertise, enhancing their utility in clinical practice.
AIM: To develop evidence-based recommendations for the diagnosis and management of gout in Australia and New Zealand as part of the multi-national 3e Initiative. METHOD: Using a formal voting process, a panel of 78 international rheumatologists selected 10 key clinical questions pertinent to the diagnosis and management of gout. An additional question was also developed by participating Australian and New Zealand rheumatologists. Each question was investigated with a systematic literature review. MEDLINE, EMBASE, Cochrane CENTRAL and abstracts from 2010 to 2011 European League Against Rheumatism and American College of Rheumatology meetings were searched in each review. Relevant studies were independently reviewed by two individuals for data extraction and synthesis and risk of bias assessment. Using this evidence, 47 Australian and New Zealand rheumatologists developed national recommendations. For each recommendation the level of agreement was assessed and the level of evidence graded. RESULT: Eleven recommendations were produced relating to the diagnosis of gout, different aspects of the management of gout, cardiovascular and renal comorbidities and the management of asymptomatic hyperuricemia. The mean level of agreement with the recommendations was 9.1 on a 1-10 scale, with 10 representing full agreement. CONCLUSION: Eleven Australian and New Zealand recommendations on the diagnosis and management of gout were developed combining systematically reviewed evidence with local expertise, enhancing their utility in clinical practice.
Authors: Diluk R W Kannangara; Garry G Graham; Daniel F B Wright; Sophie L Stocker; Ian Portek; Kevin D Pile; Murray L Barclay; Kenneth M Williams; Lisa K Stamp; Richard O Day Journal: Br J Clin Pharmacol Date: 2017-05-28 Impact factor: 4.335
Authors: Richard O Day; Lauren J Frensham; Amy D Nguyen; Melissa T Baysari; Eindra Aung; Annie Y S Lau; Nicholas Zwar; Jennifer Reath; Tracey Laba; Ling Li; Andrew McLachlan; William B Runciman; Rachelle Buchbinder; Robyn Clay-Williams; Enrico Coiera; Jeffrey Braithwaite; H Patrick McNeil; David J Hunter; Kevin D Pile; Ian Portek; Kenneth Mapson WIlliams; Johanna I Westbrook Journal: BMJ Open Date: 2017-10-16 Impact factor: 2.692
Authors: Allyce B Counsell; Amy D Nguyen; Melissa T Baysari; Diluk R W Kannangara; Andrew J McLachlan; Richard O Day Journal: BMC Fam Pract Date: 2018-05-09 Impact factor: 2.497