| Literature DB >> 25884366 |
Vivian Gama1, Mohanish Deshmukh2.
Abstract
In this and a recent issue of Molecular Cell, Liu et al. (2015) and Ichim et al. (2015) report that low levels of caspase activity triggered by limited mitochondrial outer membrane permeabilization (MOMP) promote genomic instability that drives tumorigenesis, providing a novel and unexpected link between these effectors of apoptosis and cancer initiation.Entities:
Mesh:
Year: 2015 PMID: 25884366 PMCID: PMC4879686 DOI: 10.1016/j.molcel.2015.03.035
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970