Literature DB >> 25882461

Itch, eosinophils, and autoimmunity: a novel murine model of bullous pemphigoid.

Kim B Yancey1.   

Abstract

Mice carrying a deletion in the NC14A domain of murine type XVII collagen begin scratching at age 2 months and then develop erosions, subepidermal vesicles, eosinophil-rich skin infiltrates, and autoantibodies directed against a 180 kDa skin protein that appears to be type XVII collagen. These mice represent a bullous pemphigoid animal model featuring pruritus in immunocompetent, mature, and largely unmanipulated animals.

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Year:  2015        PMID： 25882461     DOI： 10.1038/jid.2014.537

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  10 in total

1.  The extracellular domain of BPAG2 has a loop structure in the carboxy terminal flexible tail in vivo.

Authors:  S Nonaka; A Ishiko; T Masunaga; M Akiyama; K Owaribe; H Shimizu; T Nishikawa
Journal:  J Invest Dermatol       Date:  2000-11       Impact factor: 8.551

2.  Pemphigoid: clinical, histologic, immunopathologic, and therapeutic considerations.

Authors:  K B Yancey; C A Egan
Journal:  JAMA       Date:  2000-07-19       Impact factor: 56.272

Review 3.  Collagenous transmembrane proteins: recent insights into biology and pathology.

Authors:  Claus-Werner Franzke; Peter Bruckner; Leena Bruckner-Tuderman
Journal:  J Biol Chem       Date:  2004-11-23       Impact factor: 5.157

4.  Two forms of collagen XVII in keratinocytes. A full-length transmembrane protein and a soluble ectodomain.

Authors:  H Schäcke; H Schumann; N Hammami-Hauasli; M Raghunath; L Bruckner-Tuderman
Journal:  J Biol Chem       Date:  1998-10-02       Impact factor: 5.157

5.  Demonstration of the molecular shape of BP180, a 180-kDa bullous pemphigoid antigen and its potential for trimer formation.

Authors:  Y Hirako; J Usukura; Y Nishizawa; K Owaribe
Journal:  J Biol Chem       Date:  1996-06-07       Impact factor: 5.157

6.  Deletion of the major bullous pemphigoid epitope region of collagen XVII induces blistering, autoimmunization, and itching in mice.

Authors:  Tiina Hurskainen; Nina Kokkonen; Raija Sormunen; Joanna Jackow; Stefanie Löffek; Raija Soininen; Claus-Werner Franzke; Leena Bruckner-Tuderman; Kaisa Tasanen
Journal:  J Invest Dermatol       Date:  2014-10-13       Impact factor: 8.551

7.  The pathophysiology of autoimmune blistering diseases.

Authors:  Kim B Yancey
Journal:  J Clin Invest       Date:  2005-04       Impact factor: 14.808

8.  Humanization of autoantigen.

Authors:  Wataru Nishie; Daisuke Sawamura; Maki Goto; Kei Ito; Akihiko Shibaki; James R McMillan; Kaori Sakai; Hideki Nakamura; Edit Olasz; Kim B Yancey; Masashi Akiyama; Hiroshi Shimizu
Journal:  Nat Med       Date:  2007-02-25       Impact factor: 53.440

9.  A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180.

Authors:  Z Liu; L A Diaz; J L Troy; A F Taylor; D J Emery; J A Fairley; G J Giudice
Journal:  J Clin Invest       Date:  1993-11       Impact factor: 14.808

10.  Extracellular phosphorylation of collagen XVII by ecto-casein kinase 2 inhibits ectodomain shedding.

Authors:  Elena P Zimina; Anja Fritsch; Bernhard Schermer; Anastasia Yu Bakulina; Mikhail Bashkurov; Thomas Benzing; Leena Bruckner-Tuderman
Journal:  J Biol Chem       Date:  2007-06-01       Impact factor: 5.157
  10 in total
  1 in total

1.  Complement-Activating Capacity of Autoantibodies Correlates With Disease Activity in Bullous Pemphigoid Patients.

Authors:  Roxana M Chiorean; Adrian Baican; Mayson B Mustafa; Annette Lischka; Daniel-Corneliu Leucuta; Vasile Feldrihan; Michael Hertl; Cassian Sitaru
Journal:  Front Immunol       Date:  2018-11-20       Impact factor: 7.561
  1 in total

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