Literature DB >> 25881626

Predictors of treatment dropout in self-guided web-based interventions for depression: an 'individual patient data' meta-analysis.

E Karyotaki1, A Kleiboer1, F Smit1, D T Turner1, A M Pastor2, G Andersson3, T Berger4, C Botella2, J M Breton2, P Carlbring5, H Christensen6, E de Graaf7, K Griffiths8, T Donker1, L Farrer8, M J H Huibers1, J Lenndin9, A Mackinnon10, B Meyer11, S Moritz12, H Riper1, V Spek13, K Vernmark9, P Cuijpers1.   

Abstract

BACKGROUND: It is well known that web-based interventions can be effective treatments for depression. However, dropout rates in web-based interventions are typically high, especially in self-guided web-based interventions. Rigorous empirical evidence regarding factors influencing dropout in self-guided web-based interventions is lacking due to small study sample sizes. In this paper we examined predictors of dropout in an individual patient data meta-analysis to gain a better understanding of who may benefit from these interventions.
METHOD: A comprehensive literature search for all randomized controlled trials (RCTs) of psychotherapy for adults with depression from 2006 to January 2013 was conducted. Next, we approached authors to collect the primary data of the selected studies. Predictors of dropout, such as socio-demographic, clinical, and intervention characteristics were examined.
RESULTS: Data from 2705 participants across ten RCTs of self-guided web-based interventions for depression were analysed. The multivariate analysis indicated that male gender [relative risk (RR) 1.08], lower educational level (primary education, RR 1.26) and co-morbid anxiety symptoms (RR 1.18) significantly increased the risk of dropping out, while for every additional 4 years of age, the risk of dropping out significantly decreased (RR 0.94).
CONCLUSIONS: Dropout can be predicted by several variables and is not randomly distributed. This knowledge may inform tailoring of online self-help interventions to prevent dropout in identified groups at risk.

Entities:  

Keywords:  Adherence; depression; eHealth; self-help; treatment; treatment dropout; web-based interventions

Mesh:

Year:  2015        PMID: 25881626     DOI: 10.1017/S0033291715000665

Source DB:  PubMed          Journal:  Psychol Med        ISSN: 0033-2917            Impact factor:   7.723


  88 in total

1.  Good intentions are not enough: how informatics interventions can worsen inequality.

Authors:  Tiffany C Veinot; Hannah Mitchell; Jessica S Ancker
Journal:  J Am Med Inform Assoc       Date:  2018-08-01       Impact factor: 4.497

2.  User Experience Affects Dropout from Internet-Delivered Dialectical Behavior Therapy.

Authors:  Chelsey R Wilks; Qingqing Yin; Kelly L Zuromski
Journal:  Telemed J E Health       Date:  2019-09-06       Impact factor: 3.536

Review 3.  Internet-Based Cognitive-Behavioral Therapy for Depression: Current Progress and Future Directions.

Authors:  Christian A Webb; Isabelle M Rosso; Scott L Rauch
Journal:  Harv Rev Psychiatry       Date:  2017 May/Jun       Impact factor: 3.732

4.  Effects of a Psychological Internet Intervention in the Treatment of Mild to Moderate Depressive Symptoms: Results of the EVIDENT Study, a Randomized Controlled Trial.

Authors:  Jan Philipp Klein; Thomas Berger; Johanna Schröder; Christina Späth; Björn Meyer; Franz Caspar; Wolfgang Lutz; Alice Arndt; Wolfgang Greiner; Viola Gräfe; Martin Hautzinger; Kristina Fuhr; Matthias Rose; Sandra Nolte; Bernd Löwe; Gerhard Anderssoni; Eik Vettorazzi; Steffen Moritz; Fritz Hohagen
Journal:  Psychother Psychosom       Date:  2016-05-27       Impact factor: 17.659

5.  A randomized controlled feasibility trial of internet-delivered guided self-help for generalized anxiety disorder (GAD) among university students in India.

Authors:  Michelle G Newman; Nitya Kanuri; Gavin N Rackoff; Nicholas C Jacobson; Megan Jones Bell; C Barr Taylor
Journal:  Psychotherapy (Chic)       Date:  2021-12

6.  Was Eysenck right after all? A reassessment of the effects of psychotherapy for adult depression.

Authors:  P Cuijpers; E Karyotaki; M Reijnders; D D Ebert
Journal:  Epidemiol Psychiatr Sci       Date:  2018-02-28       Impact factor: 6.892

7.  Pilot randomized controlled trial of a video self-help intervention for depression based on acceptance and commitment therapy: Feasibility and acceptability.

Authors:  Brandon A Gaudiano; Carter H Davis; Ivan W Miller; Lisa Uebelacker
Journal:  Clin Psychol Psychother       Date:  2020-02-28

8.  Treatment dropout among veterans and their families: Quantitative and qualitative findings.

Authors:  Doron Amsalem; Andrea Lopez-Yianilos; Ari Lowell; Alison M Pickover; Shay Arnon; Xi Zhu; Benjamin Suarez-Jimenez; Matt Ryba; Maja Bergman; Sara Such; Hemrie Zalman; Arturo Sanchez-Lacay; Amit Lazarov; John C Markowitz; Yuval Neria
Journal:  Psychol Trauma       Date:  2021-09-16

Review 9.  Discovering Common Elements of Empirically Supported Self-Help Interventions for Depression in Primary Care: a Systematic Review.

Authors:  Naoaki Kuroda; Matthew D Burkey; Lawrence S Wissow
Journal:  J Gen Intern Med       Date:  2021-02-09       Impact factor: 5.128

10.  A randomized controlled trial on a self-guided Internet-based intervention for gambling problems.

Authors:  Lara Bücker; Josefine Gehlenborg; Steffen Moritz; Stefan Westermann
Journal:  Sci Rep       Date:  2021-06-22       Impact factor: 4.379

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