Literature DB >> 25881564

Double-Blind Randomized Controlled Trial: Injection of Autologous Blood in the Treatment of Chronic Patella Tendinopathy-A Pilot Study.

Peter Resteghini1, Tamim A Khanbhai, Shabaaz Mughal, Ziali Sivardeen.   

Abstract

OBJECTIVE: To assess the efficacy of autologous blood injections (ABIs) against saline in patients with chronic recalcitrant patella tendinopathy (PT).
DESIGN: Double-blind randomized controlled study.
SETTING: Homerton Hospital Sports Medicine department. PATIENTS: Those with a diagnosis of refractory patellar tendinopathy were recruited between March 2010 and March 2012.
INTERVENTIONS: Using 2 practitioners, patients were randomized to either receive ABIs or saline injections. MAIN OUTCOME MEASURES: All patients completed the Short-Form McGill Pain Questionnaire (MPQ), a visual analog scale (VAS), and a Victoria Institute of Sport Assessment for Patella Tendinopathy scale over a 12-month period.
RESULTS: Twenty-two patients completed the final review at 12 months and were included in the study. Subjects ranged in age from 22 and 61 years and were randomized to 11 in each ABI and saline groups. Autologous blood injection group had a mean duration of symptoms of 16.7 months, whereas that of the saline group was 19.2 months. The saline group mean VAS score was reduced from 7.9 to 4.5 at 1 month (P = 0.003) and 3.3 (P = 0.005) at 1 year. With ABI, the score was reduced from 7.5 to 4.5 (P = 0.005) at 1 month and 3.1 (P = 0.003) at 1 year. Victoria Institute of Sport Assessment for Patella Tendinopathy, MPQ, and VAS scores improved significantly in both groups.
CONCLUSIONS: This study demonstrated that both the ABI and saline groups experienced a significant improvement in symptoms. However, when the results were compared, there was no statistical difference between the 2 groups. CLINICAL RELEVANCE: This research showed that tendon fenestration is an alternative cost-effective treatment for recalcitrant PT.

Entities:  

Mesh:

Substances:

Year:  2016        PMID: 25881564     DOI: 10.1097/JSM.0000000000000184

Source DB:  PubMed          Journal:  Clin J Sport Med        ISSN: 1050-642X            Impact factor:   3.638


  2 in total

1.  Management of patellar tendinopathy: a systematic review and network meta-analysis of randomised studies.

Authors:  Dimitris Challoumas; Carles Pedret; Mairiosa Biddle; Nigel Yong Boon Ng; Paul Kirwan; Blair Cooper; Patrick Nicholas; Scott Wilson; Chris Clifford; Neal L Millar
Journal:  BMJ Open Sport Exerc Med       Date:  2021-11-29

Review 2.  Patellar Tendinopathy-Does Injection Therapy Have a Role? A Systematic Review of Randomised Control Trials.

Authors:  Shibili Nuhmani; Mohammad Ahsan; Mohd Arshad Bari; Deepak Malhotra; Wafa Hashem Al Muslem; Saad Mohammed Alsaadi; Qassim Ibrahim Muaidi
Journal:  J Clin Med       Date:  2022-04-03       Impact factor: 4.241

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.