| Literature DB >> 25880832 |
Lijuan Tang1, Si Li1, Fei Han2, Liqiang Liu1, Liguang Xu1, Wei Ma1, Hua Kuang1, Aike Li3, Libing Wang1, Chuanlai Xu4.
Abstract
Dopamine (DA) is a neurotransmitter which plays a key role in the life science. Self-assembled Au@Ag nanorod dimers based on aptamers were developed for ultrasensitive dopamine detection. The electronic field was significantly enhanced by the addition of silver shell coating on the surface of Au NR dimer. The results displayed that Au@Ag NR dimers were ideal building blocks for constructing the SERS substrates with prominent Raman enhancement effects. It was found that with using this Surface-enhanced Raman scattering (SERS)-encoded this sensing system, a limit of detection of 0.006 pM and a wide linear range of 0.01-10 pM for dopamine detection were obtained. Our work open up a new avenue for the diagnosis and drug-discovery programs.Entities:
Keywords: Au@Ag nanorod dimers; Detection; Dopamine; SERS
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Year: 2015 PMID： 25880832 DOI： 10.1016/j.bios.2015.04.013
Source DB: PubMed Journal: Biosens Bioelectron ISSN： 0956-5663 Impact factor: 10.618