Literature DB >> 2587985

Purification, cloning, and expression of ciliary neurotrophic factor (CNTF).

L F Lin1, D Mismer, J D Lile, L G Armes, E T Butler, J L Vannice, F Collins.   

Abstract

Ciliary neurotrophic factor (CNTF) is one of a small number of proteins with neurotrophic activities distinct from nerve growth factor (NGF). CNTF has now been purified and cloned and the primary structure of CNTF from rabbit sciatic nerve has been determined. Biologically active CNTF has been transiently expressed from a rabbit complementary DNA clone. CNTF is a neural effector without significant sequence homologies to any previously reported protein.

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Year:  1989        PMID： 2587985     DOI： 10.1126/science.2587985

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  71 in total

1.  Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice.

Authors:  M Sendtner; R Götz; B Holtmann; H Thoenen
Journal:  J Neurosci       Date:  1997-09-15       Impact factor: 6.167

Review 2.  Neuronal cell cultures: a tool for investigations in developmental neurobiology.

Authors:  A Cestelli; G Savettieri; G Salemi; I Di Liegro
Journal:  Neurochem Res       Date:  1992-12       Impact factor: 3.996

3.  A ciliary neuronotrophic factor from peripheral nerve and smooth muscle which is not retrogradely transported.

Authors:  P J Smet; I K Abrahamson; R E Ressom; R A Rush
Journal:  Neurochem Res       Date:  1991-06       Impact factor: 3.996

4.  IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants.

Authors:  Francois Rousseau; Laetitia Basset; Josy Froger; Nathalie Dinguirard; Sylvie Chevalier; Hugues Gascan
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-25       Impact factor: 11.205

5.  Blot and culture analysis of neuronotrophic factors in nerve regeneration chamber fluids.

Authors:  D J Bates; J A Ranford; D C Mangelsdorf
Journal:  Neurochem Res       Date:  1991-06       Impact factor: 3.996

6.  Structure-function studies of human ciliary neurotrophic factor.

Authors:  A Negro; V Corsa; G Corona; C Grandi; S D Skaper; L Callegaro
Journal:  Neurochem Res       Date:  1994-02       Impact factor: 3.996

7.  A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury.

Authors:  C G Winter; Y Saotome; S W Levison; D Hirsh
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

8.  Human ciliary neurotrophic factor: a structure-function analysis.

Authors:  A Krüttgen; J Grötzinger; G Kurapkat; J Weis; R Simon; M Thier; M Schröder; P Heinrich; A Wollmer; M Comeau
Journal:  Biochem J       Date:  1995-07-01       Impact factor: 3.857

9.  Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo.

Authors:  T Hagg; S Varon
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

10.  CNTF receptor subunit α as a marker for glioma tumor-initiating cells and tumor grade: laboratory investigation.

Authors:  Jie Lu; Alexander Ksendzovsky; Chunzhang Yang; Gautam U Mehta; Raymund L Yong; Robert J Weil; Deric M Park; Harry M Mushlin; Xueping Fang; Brian M Balgley; Dae-Hee Lee; Cheng S Lee; Russell R Lonser; Zhengping Zhuang
Journal:  J Neurosurg       Date:  2012-10-12       Impact factor: 5.115
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