Literature DB >> 25877838

Sodium imaging as a marker of tissue injury in patients with multiple sclerosis.

M Inglese1, N Oesingmann2, W Zaaraoui3, J P Ranjeva3, L Fleysher4.   

Abstract

Recent studies have suggested that intra-axonal sodium accumulation contribute to axonal degeneration in patients with MS. Advances in MRI hardware and software allow acquisition of brain sodium signal in vivo. This review begins with a summary of the experimental evidence for impairment of sodium homeostasis in MS. Then, MRI methods for sodium acquisition are reviewed and the application of the techniques in patients with MS is discussed. Sodium imaging and ultra-high field MRI have the potential to provide tissue-specific markers of neurodegeneration in MS.
Copyright © 2013 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Multiple Sclerosis; Multiple-quantum filtering; Sodium imaging; Ultra-high magnetic field

Year:  2013        PMID： 25877838     DOI： 10.1016/j.msard.2013.03.009

Source DB:  PubMed          Journal:  Mult Scler Relat Disord        ISSN： 2211-0348            Impact factor:   4.339


  3 in total

Review 1.  Imaging outcome measures of neuroprotection and repair in MS: A consensus statement from NAIMS.

Authors:  Jiwon Oh; Daniel Ontaneda; Christina Azevedo; Eric C Klawiter; Martina Absinta; Douglas L Arnold; Rohit Bakshi; Peter A Calabresi; Ciprian Crainiceanu; Blake Dewey; Leorah Freeman; Susan Gauthier; Roland Henry; Mathilde Inglese; Shannon Kolind; David K B Li; Caterina Mainero; Ravi S Menon; Govind Nair; Sridar Narayanan; Flavia Nelson; Daniel Pelletier; Alexander Rauscher; William Rooney; Pascal Sati; Daniel Schwartz; Russell T Shinohara; Ian Tagge; Anthony Traboulsee; Yi Wang; Youngjin Yoo; Tarek Yousry; Yunyan Zhang; Nancy L Sicotte; Daniel S Reich
Journal:  Neurology       Date:  2019-02-20       Impact factor: 9.910

2.  Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis.

Authors:  Shahamat Tauhid; Renxin Chu; Rahul Sasane; Bonnie I Glanz; Mohit Neema; Jennifer R Miller; Gloria Kim; James E Signorovitch; Brian C Healy; Tanuja Chitnis; Howard L Weiner; Rohit Bakshi
Journal:  J Neurol       Date:  2015-07-24       Impact factor: 4.849

Review 3.  Advances in brain imaging in multiple sclerosis.

Authors:  Rosa Cortese; Sara Collorone; Olga Ciccarelli; Ahmed T Toosy
Journal:  Ther Adv Neurol Disord       Date:  2019-06-27       Impact factor: 6.570
  3 in total

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