Literature DB >> 2587719

[Gadolinium-DTPA as an oral contrast medium in magnetic resonance tomography].

S Kaminsky, M Laniado, M Gogoll, W Kornmesser, W Clauss, R Felix.   

Abstract

80 patients with tumorous or inflammatory abdominal diseases were investigated with the paramagnetic MRT contrast medium Gadolinium-DTPA (Gd-DTPA, 1 mM, 15 g/l mannitol, 6-16 ml per kg body weight) at 0.5 Tesla with T1-, proton density and T2-weighted SE- and gradient-echo sequences. 53 patients were investigated also before the contrast medium was given. Gd-DTPA showed hyperintense labelling of the intestinal loops that was detectable with all excitation sequences and was constant over all phases of the passage. In 35 of the 53 patients investigated before and after application of Gd-DTPA lesions were better imaged while diagnostic improvements, especially for smaller lesions, were achieved in 5 of 80 patients. One third of the patients reported slight meteorism and diarrhoea after the mannitol-containing suspension.

Entities:  

Mesh:

Substances:

Year:  1989        PMID: 2587719

Source DB:  PubMed          Journal:  Radiol Diagn (Berl)        ISSN: 0033-8354


  1 in total

1.  Gd-DTPA as an intestinal contrast agent for MR imaging of the lower abdomen: phase III clinical trial.

Authors:  L Vlahos; A Gouliamos; W Clauss; A Kalovidouris; A Athanasopoulou; A Petroulakis; A Hadjiioannou; C Papavasiliou
Journal:  Gastrointest Radiol       Date:  1992
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.