Literature DB >> 25875898

Can Therapeutic Hypothermia Be Guided by Advanced Neuromonitoring in Neurocritical Care Patients? A Review.

Alois Josef Schiefecker1, Ronny Beer1, Gregor Broessner1, Mario Kofler1, Erich Schmutzhard1, Raimund Helbok1.   

Abstract

The impact of therapeutic hypothermia (TH) on long-term neurological outcome is still controversial. Data on the effects of TH on brain homeostasis are mostly derived from experimental research. Invasive multimodal neuromonitoring techniques may provide additional insight into pathophysiological changes associated with primary or secondary brain injury in humans. In this study we describe the principles of multimodal neuromonitoring and its potential in the clinical setting of TH. We call for more research using multimodal neuromonitoring techniques in patients undergoing TH to optimize cooling and rewarming strategies.

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Year:  2015        PMID： 25875898     DOI： 10.1089/ther.2014.0028

Source DB:  PubMed          Journal:  Ther Hypothermia Temp Manag        ISSN： 2153-7658            Impact factor:   1.286


  5 in total

1.  Mild Hypothermia Combined with Hydrogen Sulfide Treatment During Resuscitation Reduces Hippocampal Neuron Apoptosis Via NR2A, NR2B, and PI3K-Akt Signaling in a Rat Model of Cerebral Ischemia-Reperfusion Injury.

Authors:  Hai-Bin Dai; Miao-Miao Xu; Jia Lv; Xiang-Jun Ji; Si-Hai Zhu; Ru-Meng Ma; Xiao-Lei Miao; Man-Lin Duan
Journal:  Mol Neurobiol       Date:  2015-09-09       Impact factor: 5.590

2.  Enteral nutrition increases interstitial brain glucose levels in poor-grade subarachnoid hemorrhage patients.

Authors:  Mario Kofler; Alois J Schiefecker; Ronny Beer; Maxime Gaasch; Paul Rhomberg; John Stover; Bettina Pfausler; Claudius Thomé; Erich Schmutzhard; Raimund Helbok
Journal:  J Cereb Blood Flow Metab       Date:  2017-03-21       Impact factor: 6.200

3.  Brain temperature but not core temperature increases during spreading depolarizations in patients with spontaneous intracerebral hemorrhage.

Authors:  Alois J Schiefecker; Mario Kofler; Max Gaasch; Ronny Beer; Iris Unterberger; Bettina Pfausler; Gregor Broessner; Peter Lackner; Paul Rhomberg; Elke Gizewski; Werner O Hackl; Miriam Mulino; Martin Ortler; Claudius Thome; Erich Schmutzhard; Raimund Helbok
Journal:  J Cereb Blood Flow Metab       Date:  2017-04-24       Impact factor: 6.200

4.  Neuroglucopenia and Metabolic Distress in Two Patients with Viral Meningoencephalitis: A Microdialysis Study.

Authors:  Mario Kofler; Alois Schiefecker; Ronny Beer; Florian Sohm; Gregor Broessner; Paul Rhomberg; Peter Lackner; Bettina Pfausler; Claudius Thomé; Erich Schmutzhard; Raimund Helbok
Journal:  Neurocrit Care       Date:  2016-10       Impact factor: 3.210

5.  Hyperpyrexia in life-threatening central nervous system infection - It is the timepoint of fever which matters: A plea to select the best timing and optimal methods of temperature management.

Authors:  Schmutzhard Erich; Pfausler Bettina
Journal:  Brain Circ       Date:  2017-12-29
  5 in total

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