| Literature DB >> 25875448 |
Rajib Deb1, Basavaraj Sajjanar2, Umesh Singh3, Rani Alex3, T V Raja3, Rafeeque R Alyethodi3, Sushil Kumar3, Gyanendra Sengar3, Sheetal Sharma3, Rani Singh3, B Prakash3.
Abstract
Na+/K+-ATPase is an integral membrane protein composed of a large catalytic subunit (alpha), a smaller glycoprotein subunit (beta), and gamma subunit. The beta subunit is essential for ion recognition as well as maintenance of the membrane integrity. Present study was aimed to analyze the expression pattern of ATPase beta subunit genes (ATPase B1, ATPase B2, and ATPase B3) among the crossbred bulls under different ambient temperatures (20-44 °C). The present study was also aimed to look into the relationship of HSP70 with the ATPase beta family genes. Our results demonstrated that among beta family genes, transcript abundance of ATPase B1 and ATPase B2 is significantly (P < 0.05) higher during the thermal stress. Pearson correlation coefficient analysis revealed that the expression of ATPase Β1, ATPase B2, and ATPase B3 is highly correlated (P < 0.01) with HSP70, representing that the change in the expression pattern of these genes is positive and synergistic. These may provide a foundation for understanding the mechanisms of ATPase beta family genes for cellular thermotolerance in cattle.Entities:
Keywords: ATPase B1; ATPase B2; ATPase B3; HSP70
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Year: 2015 PMID： 25875448 DOI： 10.1007/s00484-015-0986-x
Source DB: PubMed Journal: Int J Biometeorol ISSN： 0020-7128 Impact factor: 3.787