Literature DB >> 25874845

Craniovertebral tuberculosis in children: experience of 23 cases and proposal for a new classification.

Sandip Chatterjee1, Amitabha Das.   

Abstract

PURPOSE: The aim of this study was to review cases of paediatric patients with craniovertebral junction (CVJ) tuberculosis with a view to try and stratify the cases into different groups which would help plan treatment and hence develop a protocol for treatment of a fairly uncommon condition still widely seen in the developing world.
METHODS: Twenty-three cases of paediatric craniovertebral tuberculosis had their clinical features and radiology reviewed. The treatment plan in each case was analyzed according to their presentation. The results of treatment after 1 year were assessed in each case.
RESULTS: The clinical presentations varied from neck pain with hypoglossal nerve palsy to frank spastic quadriparesis, and frank instability at the atlanto-axial junction was seen in five out of 23 patients. Cold abscesses were seen in 18/23 cases, and severe torticollis was the presentation in 6/23. We graded the children with this condition into three groups: 1) those with instability and gross neurodeficit who required early operative intervention (1 needed trans-oral decompression with posterior fixation and 4 required posterior fixation) 2) those who had severe torticollis and large cold abscesses who were treated with trans-oral aspiration of cold abscess followed by neck immobilization (6/23) and 3) those who did not have significant neck muscle spasm or torticollis and who were treated with immobilization alone (12/23). Only one child in group 3 required delayed intervention for instability which developed after completion of the course of anti-tubercular medication.
CONCLUSIONS: We concluded that children with craniovertebral tuberculosis should be treated according to their clinical presentation coupled with evidence of radiological instability. Those with gross deficit and instability need early stabilization, those with minimal deficit and no instability but severe pain or torticollis need aspiration of the cold abscess with external immobilization, whereas those without deficit, instability or severe pain may be managed by external orthoses alone. Of course, medical treatment for tuberculosis is necessary in each case.

Entities:  

Mesh:

Year:  2015        PMID: 25874845     DOI: 10.1007/s00381-015-2695-5

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  26 in total

1.  Management of tuberculomas of the craniovertebral junction.

Authors:  R J Edwards; K M David; H A Crockard
Journal:  Br J Neurosurg       Date:  2000-02       Impact factor: 1.596

2.  Evaluation of radiological investigations in spinal tuberculosis.

Authors:  K M al Arabi; M W al Sebai; M al Chakaki
Journal:  Int Orthop       Date:  1992       Impact factor: 3.075

3.  Cervical caries with retropharyngeal abscess.

Authors:  A SINHA; P KAKAR
Journal:  Arch Otolaryngol       Date:  1963-07

4.  Tuberculous atlanto-axial dislocation (with remarks on the mechanism of dislocation).

Authors:  S K Pandya
Journal:  Neurol India       Date:  1971-09       Impact factor: 2.117

5.  Computed tomography of vertebral tuberculosis: patterns of bone destruction.

Authors:  R Jain; S Sawhney; M Berry
Journal:  Clin Radiol       Date:  1993-03       Impact factor: 2.350

6.  Surgical management and outcome of tuberculous atlantoaxial dislocation: a 15-year experience.

Authors:  Sanjiv Sinha; Anil Kumar Singh; Vikas Gupta; Daljit Singh; Masakazu Takayasu; Jun Yoshida
Journal:  Neurosurgery       Date:  2003-02       Impact factor: 4.654

7.  Spinal tuberculosis: a diagnostic and management challenge.

Authors:  E S Nussbaum; G L Rockswold; T A Bergman; D L Erickson; E L Seljeskog
Journal:  J Neurosurg       Date:  1995-08       Impact factor: 5.115

8.  Imaging in children with spinal tuberculosis. A comparison of radiography, computed tomography and magnetic resonance imaging.

Authors:  E B Hoffman; J H Crosier; B J Cremin
Journal:  J Bone Joint Surg Br       Date:  1993-03

9.  Craniocervical junction tuberculosis: a rare but dangerous disease.

Authors:  I U Kanaan; M Ellis; T Safi; M Z Al Kawi; R Coates
Journal:  Surg Neurol       Date:  1999-01

10.  Craniovertebral junction tuberculosis: a new comprehensive therapeutic strategy.

Authors:  Ramesh Teegala; Pradyuth Kumar; Shashank S Kale; Bhawani S Sharma
Journal:  Neurosurgery       Date:  2008-11       Impact factor: 4.654

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.