Literature DB >> 25874738

[A 73-year-old female patient after liver and kidney transplantation with dull pain in the epigastrium and recurrent epistaxis].

M E Zinser1, H J F Salzer, A Stein, M von Petersdorff, A Koops, J Holzhüter.   

Abstract

A 73-year-old female patient who had received a liver and kidney transplantation presented with symptomatic pancytopenia and right-sided upper abdominal pain. The histological investigation of a bone marrow biopsy showed the extremely rare manifestation of a disseminated Merkel cell carcinoma with infiltration of the bone marrow and suppression of hematopoiesis. Also a Coombs test positive hemolytic anemia did not show a significant response to high-dose steroid therapy. Palliative chemotherapy with carboplatin and etoposide at reduced dosage had to be terminated due to deterioration of the patient's general condition. The patient died 2 days after initiation of chemotherapy.

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Year:  2015        PMID: 25874738     DOI: 10.1007/s00108-015-3700-5

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  10 in total

1.  Images in haematology. Heavy bone marrow involvement with metastatic Merkel cell tumour in an immunosuppressed renal transplant recipient.

Authors:  K L Morris; Bronwyn Williams; G A Kennedy
Journal:  Br J Haematol       Date:  2005-01       Impact factor: 6.998

2.  'Leukaemic' presentation of metastatic Merkel cell carcinoma.

Authors:  Constantine S Tam; Paul Turner; Catriona McLean; Susan Whitehead; Merrole Cole-Sinclair
Journal:  Br J Haematol       Date:  2005-05       Impact factor: 6.998

3.  Metastatic Merkel cell carcinoma involving the bone marrow with chronic lymphocytic leukemia mimicking Richter transformation.

Authors:  Huan-You Wang; Ahmed S Shabaik
Journal:  Blood       Date:  2013-10-17       Impact factor: 22.113

4.  [Comparison of two different tissue decalcification methods for immunohistochemistry].

Authors:  Juan Du; Jian-ying Liu; Jing Su
Journal:  Beijing Da Xue Xue Bao Yi Xue Ban       Date:  2011-04-18

5.  Pancytopaenia secondary to bone marrow dissemination of Merkel cell carcinoma in a patient with Waldenström macroglobulinaemia.

Authors:  Christelle Le Gall-Ianotto; Nolwenn Coquart; Jean-Christophe Ianotto; Gaelle Guillerm; Camille Grall; Isabelle Quintin-Roue; Veronique Marion; Matthieu Greco; Christian Berthou; Laurent Misery
Journal:  Eur J Dermatol       Date:  2011 Jan-Feb       Impact factor: 3.328

Review 6.  Metastatic Merkel cell carcinoma in the bone marrow of a patient with plasma cell myeloma and therapy-related myelodysplastic syndrome.

Authors:  Megan Kielt Kressin; Annette S Kim
Journal:  Int J Clin Exp Pathol       Date:  2012-10-20

7.  Collision tumor composed of Merkel cell carcinoma and lentigo maligna melanoma.

Authors:  Seth B Forman; Dennis A Vidmar; Tammie C Ferringer
Journal:  J Cutan Pathol       Date:  2008-02       Impact factor: 1.587

Review 8.  [Merkel cell carcinoma--clinically often misjudged].

Authors:  H Weisser; W Hartschuh; A Greiner; M Bischof; A Enk; P Helmbold
Journal:  Dtsch Med Wochenschr       Date:  2007-07-30       Impact factor: 0.628

9.  Merkel cell carcinoma: a clinicopathologic study with prognostic implications.

Authors:  Ryan T Mott; Bruce R Smoller; Michael B Morgan
Journal:  J Cutan Pathol       Date:  2004-03       Impact factor: 1.587

Review 10.  Merkel Cell Carcinoma: Epidemiology, Target, and Therapy.

Authors:  Mathew P Hughes; Matthew E Hardee; Lynn A Cornelius; Laura F Hutchins; Jurgen C Becker; Ling Gao
Journal:  Curr Dermatol Rep       Date:  2014-01-22
  10 in total

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