| Literature DB >> 25874738 |
M E Zinser1, H J F Salzer, A Stein, M von Petersdorff, A Koops, J Holzhüter.
Abstract
A 73-year-old female patient who had received a liver and kidney transplantation presented with symptomatic pancytopenia and right-sided upper abdominal pain. The histological investigation of a bone marrow biopsy showed the extremely rare manifestation of a disseminated Merkel cell carcinoma with infiltration of the bone marrow and suppression of hematopoiesis. Also a Coombs test positive hemolytic anemia did not show a significant response to high-dose steroid therapy. Palliative chemotherapy with carboplatin and etoposide at reduced dosage had to be terminated due to deterioration of the patient's general condition. The patient died 2 days after initiation of chemotherapy.Entities:
Mesh:
Substances:
Year: 2015 PMID: 25874738 DOI: 10.1007/s00108-015-3700-5
Source DB: PubMed Journal: Internist (Berl) ISSN: 0020-9554 Impact factor: 0.743