Literature DB >> 25874559

Pertussis in infants less than 6 months of age and household contacts, Italy, April 2014.

Michela Sali1, Gabriele Buttinelli, Cecilia Fazio, Paola Vacca, Marilena La Sorda, Anna Carannante, Teresa Spanu, Piero Valentini, Paola Stefanelli.   

Abstract

We report pertussis cases in 4 infants less than 6 months admitted with symptoms compatible with pertussis to the intensive care unit of the Università Cattolica del Sacro Cuore in Rome, April 2014. Realtime PCR confirmed pertussis diagnosis for the 4 infants, 2 of them were cousins, and for the household contacts of 1 of them. Analysis of pertussis toxin, its promoter and pertactin was also performed. First of all, this report emphasizes the need to investigate household contact of infants with pertussis; secondly, to evaluate the selective vaccination of household members of newborns as an effective program to reduce pertussis in infants.

Entities:  

Keywords:  Italy; household contacts; infant; pertussis; prn, pertactin; ptxA, subunit S1 of the pertussis toxin; ptxP, promoter of the pertussis toxin gene; vaccine

Mesh：

Substances：

Year:  2015        PMID： 25874559      PMCID： PMC4514279          DOI： 10.1080/21645515.2015.1019190

Source DB:  PubMed          Journal:  Hum Vaccin Immunother        ISSN： 2164-5515            Impact factor:   3.452


  18 in total

1.  Antigenic variants in Bordetella pertussis strains isolated from vaccinated and unvaccinated children.

Authors:  Paola Mastrantonio; Patrizia Spigaglia; Hans van Oirschot; Han G J van der Heide; Kees Heuvelman; Paola Stefanelli; Frits R Mooi
Journal:  Microbiology       Date:  1999-08       Impact factor: 2.777

2.  Genotypic variation in the Bordetella pertussis virulence factors pertactin and pertussis toxin in historical and recent clinical isolates in the United Kingdom.

Authors:  N K Fry; S Neal; T G Harrison; E Miller; R Matthews; R C George
Journal:  Infect Immun       Date:  2001-09       Impact factor: 3.441

3.  Multiple-locus variable-number tandem repeat analysis of Dutch Bordetella pertussis strains reveals rapid genetic changes with clonal expansion during the late 1990s.

Authors:  Leo M Schouls; Han G J van der Heide; Luc Vauterin; Paul Vauterin; Frits R Mooi
Journal:  J Bacteriol       Date:  2004-08       Impact factor: 3.490

4.  How increased pertussis vaccination coverage is changing the epidemiology of pertussis in Italy.

Authors:  M Cristina Rota; Fortunato D'Ancona; Marco Massari; Donatella Mandolini; Anna Giammanco; Patrizia Carbonari; Stefania Salmaso; Marta Luisa Ciofi degli Atti
Journal:  Vaccine       Date:  2005-08-08       Impact factor: 3.641

Review 5.  Epidemiology of pertussis in Italy: disease trends over the last century.

Authors:  M V Gonfiantini; E Carloni; F Gesualdo; E Pandolfi; E Agricola; E Rizzuto; S Iannazzo; M L Ciofi Degli Atti; A Villani; A E Tozzi
Journal:  Euro Surveill       Date:  2014-10-09

Review 6.  Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies.

Authors:  Seema Mattoo; James D Cherry
Journal:  Clin Microbiol Rev       Date:  2005-04       Impact factor: 26.132

7.  Polymorphism in the Bordetella pertussis virulence factors P.69/pertactin and pertussis toxin in The Netherlands: temporal trends and evidence for vaccine-driven evolution.

Authors:  F R Mooi; H van Oirschot; K Heuvelman; H G van der Heide; W Gaastra; R J Willems
Journal:  Infect Immun       Date:  1998-02       Impact factor: 3.441

8.  Role of PCR in the diagnosis of pertussis infection in infants: 5 years' experience of provision of a same-day real-time PCR service in England and Wales from 2002 to 2007.

Authors:  Norman K Fry; John Duncan; Karen Wagner; Oceanis Tzivra; Nita Doshi; David J Litt; Natasha Crowcroft; Elizabeth Miller; Robert C George; Timothy G Harrison
Journal:  J Med Microbiol       Date:  2009-06-15       Impact factor: 2.472

9.  Infant pertussis: who was the source?

Authors:  Kristine M Bisgard; F Brian Pascual; Kristen R Ehresmann; Claudia A Miller; Christy Cianfrini; Charles E Jennings; Catherine A Rebmann; Julie Gabel; Stephanie L Schauer; Susan M Lett
Journal:  Pediatr Infect Dis J       Date:  2004-11       Impact factor: 2.129

10.  Protecting newborns from pertussis - the challenge of complete cocooning.

Authors:  Pascal Urwyler; Ulrich Heininger
Journal:  BMC Infect Dis       Date:  2014-07-17       Impact factor: 3.090
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  3 in total

Review 1.  Pertussis: Microbiology, Disease, Treatment, and Prevention.

Authors:  Paul E Kilgore; Abdulbaset M Salim; Marcus J Zervos; Heinz-Josef Schmitt
Journal:  Clin Microbiol Rev       Date:  2016-07       Impact factor: 26.132

2.  Epidemiology of pertussis in two Ibero-American countries with different vaccination policies: lessons derived from different surveillance systems.

Authors:  Rubén Solano; Josefa Masa-Calles; Zacarías Garib; Patricia Grullón; Sandy L Santiago; Altagracia Brache; Ángela Domínguez; Joan A Caylà
Journal:  BMC Public Health       Date:  2016-11-22       Impact factor: 3.295

3.  Severe pertussis infection in infants less than 6 months of age: Clinical manifestations and molecular characterization.

Authors:  Paola Stefanelli; Gabriele Buttinelli; Paola Vacca; Alberto E Tozzi; Fabio Midulla; Rita Carsetti; Giorgio Fedele; Alberto Villani; Carlo Concato
Journal:  Hum Vaccin Immunother       Date:  2017-01-27       Impact factor: 3.452
  3 in total

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