Literature DB >> 25873835

Dazed, confused, and asystolic: possible signs of anti-N-methyl-D-aspartate receptor encephalitis.

Boback Ziaeian, Kamran Shamsa.   

Abstract

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare panencephalitis that can present with severe cardiac dysrhythmias. We present a case of a 19-year-old woman with no significant medical history who presented with progressive changes in mental status and profound ictal asystole that necessitated the placement of an external temporary pacemaker. She was diagnosed with and treated for anti-NMDA receptor encephalitis, and she recovered after a prolonged and complicated hospitalization. We review the pathophysiology and management of anti-NMDA receptor encephalitis, as well as its cardiac manifestations.

Entities:  

Keywords:  Anti-N-methyl-D-aspartate receptor encephalitis/complications/diagnosis/etiology/therapy; asystole; delirium, dementia, amnestic, cognitive disorders/immunology; disease progression; female; heart block; immunosuppressive agents/therapeutic use; immunotherapy/methods; ovarian neoplasms/complications; paraneoplastic syndromes, nervous system; syncope, vasovagal/etiology; teratoma/complications

Mesh:

Year:  2015        PMID: 25873835      PMCID: PMC4382890          DOI: 10.14503/THIJ-13-3987

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  8 in total

Review 1.  Anti-NMDA receptor encephalitis. The disorder, the diagnosis and the immunobiology.

Authors:  Harry E Peery; Gregory S Day; Shannon Dunn; Marvin J Fritzler; Harald Prüss; Claire De Souza; Asif Doja; Karen Mossman; Lothar Resch; Chenjie Xia; Boris Sakic; Larry Belbeck; Warren G Foster
Journal:  Autoimmun Rev       Date:  2012-03-11       Impact factor: 9.754

2.  Anti-NMDA receptor encephalitis: diagnosis, psychiatric presentation, and treatment.

Authors:  Meredith R Chapman; Holly E Vause
Journal:  Am J Psychiatry       Date:  2011-03       Impact factor: 18.112

3.  Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study.

Authors:  Maarten J Titulaer; Lindsey McCracken; Iñigo Gabilondo; Thaís Armangué; Carol Glaser; Takahiro Iizuka; Lawrence S Honig; Susanne M Benseler; Izumi Kawachi; Eugenia Martinez-Hernandez; Esther Aguilar; Núria Gresa-Arribas; Nicole Ryan-Florance; Abiguei Torrents; Albert Saiz; Myrna R Rosenfeld; Rita Balice-Gordon; Francesc Graus; Josep Dalmau
Journal:  Lancet Neurol       Date:  2013-01-03       Impact factor: 44.182

4.  Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma.

Authors:  Josep Dalmau; Erdem Tüzün; Hai-yan Wu; Jaime Masjuan; Jeffrey E Rossi; Alfredo Voloschin; Joachim M Baehring; Haruo Shimazaki; Reiji Koide; Dale King; Warren Mason; Lauren H Sansing; Marc A Dichter; Myrna R Rosenfeld; David R Lynch
Journal:  Ann Neurol       Date:  2007-01       Impact factor: 10.422

Review 5.  NMDA receptor antibody encephalitis.

Authors:  Sarosh R Irani; Angela Vincent
Journal:  Curr Neurol Neurosci Rep       Date:  2011-06       Impact factor: 5.081

6.  Anti-NMDA receptor encephalitis associated with ictal asystole.

Authors:  Mark Lee; Nicholas Lawn; David Prentice; Josephine Chan
Journal:  J Clin Neurosci       Date:  2011-10-10       Impact factor: 1.961

7.  Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies.

Authors:  Josep Dalmau; Amy J Gleichman; Ethan G Hughes; Jeffrey E Rossi; Xiaoyu Peng; Meizan Lai; Scott K Dessain; Myrna R Rosenfeld; Rita Balice-Gordon; David R Lynch
Journal:  Lancet Neurol       Date:  2008-10-11       Impact factor: 44.182

Review 8.  Seizures and syncope: anatomic basis and diagnostic considerations.

Authors:  Jeffrey W Britton; Eduardo Benarroch
Journal:  Clin Auton Res       Date:  2006-02       Impact factor: 4.435

  8 in total
  5 in total

Review 1.  [Intensive care aspects of autoimmune encephalitis].

Authors:  A Günther; J Schubert; O W Witte; D Brämer
Journal:  Med Klin Intensivmed Notfmed       Date:  2019-08-27       Impact factor: 0.840

2.  Gamma-aminobutyric acid-B limbic encephalitis and asystolic cardiac arrest: a case report.

Authors:  Christopher A Ovens; Angelo Jayamanne; Andrew Duggins
Journal:  J Med Case Rep       Date:  2017-12-29

3.  A Case of Severe Anti-N-Methyl D-Aspartate (Anti-NMDA) Receptor Encephalitis with Refractory Autonomic Instability and Elevated Intracranial Pressure.

Authors:  Nooshin Salehi; Adam K Yuan; Gizelle Stevens; Ruby Koshy; Walter F Klein
Journal:  Am J Case Rep       Date:  2018-10-12

4.  Nursing care in anti-N-methyl-D-aspartate receptor encephalitis: A case series.

Authors:  Li Yang; Qian Jiang; Hongzhi Guan; Haixin Bo
Journal:  Medicine (Baltimore)       Date:  2019-11       Impact factor: 1.817

5.  Profound Autonomic Instability Complicated by Multiple Episodes of Cardiac Asystole and Refractory Bradycardia in a Patient with Anti-NMDA Encephalitis.

Authors:  Stephanie R Mehr; Roy C Neeley; Melissa Wiley; Avinash B Kumar
Journal:  Case Rep Neurol Med       Date:  2016-04-17
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.