Literature DB >> 25872605

[Fatal outcome for a patient in treatment with dabigatran suffering a subtrochanteric femoral fracture].

Lasse Enkebølle Rasmussen1, Bjarke L Viberg, Anton Pottegård.   

Abstract

An 82-year-old woman in treatment with the thrombin inhibitor dabigatran etexilate (a new oral anticoagulant (NOAC)) was admitted with a subtrochanteric femoral fracture and surgery was initiated 15 hours after admittance. She had a blood loss of 6,000 ml and died the next morning from multi-organ failure. In 2013 1.8% of hip fracture patients in Funen received NOACs. Surgery is recommended within 24 hours for hip fracture patients to reduce mortality, but patients in treatment with NOACs should wait at least 48 hours before major surgery. Care should be taken when prescribing NOACs to patients with high risk of falling.

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Year:  2015        PMID: 25872605

Source DB:  PubMed          Journal:  Ugeskr Laeger        ISSN: 0041-5782


  1 in total

1.  Safety profile of the direct oral anticoagulants: an analysis of the WHO database of adverse drug reactions.

Authors:  Luca Monaco; Chiara Biagi; Valentino Conti; Mauro Melis; Monia Donati; Mauro Venegoni; Alberto Vaccheri; Domenico Motola
Journal:  Br J Clin Pharmacol       Date:  2017-03-19       Impact factor: 4.335

  1 in total

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