T Schlögl1, J Schwab1, M A Weber1, B Witzenbichler1, M A Russ2. 1. Klinik für Innere Medizin I, Helios-Amperklinikum Dachau, Krankenhausstr. 15, 85221, Dachau, Deutschland. 2. Klinik für Innere Medizin I, Helios-Amperklinikum Dachau, Krankenhausstr. 15, 85221, Dachau, Deutschland. martin.russ@posteo.de.
Abstract
BACKGROUND: The favorable effect of mild therapeutic hypothermia (MTH) on neurologic status as well as on overall survival was shown in several trials; however, MTH is not readily implemented in daily routine. OBJECTIVE: We examined the effect of the implementation of MTH on neurologic outcome and overall survival in an emergency care hospital. STUDY DESIGN AND METHODS: The data of 68 patients between 09/2010 and 11/2011 who received MTH for 24 h at 33 °C after cardiopulmonary resuscitation (CPR) were compared with prospectively collected data from 180 patients before introduction of MTH (2001-2006). Survival and neurological status at discharge were determined using the Glasgow-Pittsburgh Cerebral Performance Categories (CPC). RESULTS: MTH raised the percentage of patients with a CPC score of 1 or 2 from 70 % to 85 %. Furthermore, survival increased from 47/180 (26 %) between 01/2000 and 01/2006 to 27/68 (40 %) between 09/2010 and 11/2011. DISCUSSION: Implementation of MTH leads to improved neurological status and overall survival after CPR.
BACKGROUND: The favorable effect of mild therapeutic hypothermia (MTH) on neurologic status as well as on overall survival was shown in several trials; however, MTH is not readily implemented in daily routine. OBJECTIVE: We examined the effect of the implementation of MTH on neurologic outcome and overall survival in an emergency care hospital. STUDY DESIGN AND METHODS: The data of 68 patients between 09/2010 and 11/2011 who received MTH for 24 h at 33 °C after cardiopulmonary resuscitation (CPR) were compared with prospectively collected data from 180 patients before introduction of MTH (2001-2006). Survival and neurological status at discharge were determined using the Glasgow-Pittsburgh Cerebral Performance Categories (CPC). RESULTS:MTH raised the percentage of patients with a CPC score of 1 or 2 from 70 % to 85 %. Furthermore, survival increased from 47/180 (26 %) between 01/2000 and 01/2006 to 27/68 (40 %) between 09/2010 and 11/2011. DISCUSSION: Implementation of MTH leads to improved neurological status and overall survival after CPR.
Authors: Sebastian Wolfrum; Peter W Radke; Tobias Pischon; Stefan N Willich; Heribert Schunkert; Volkhard Kurowski Journal: Resuscitation Date: 2006-11-13 Impact factor: 5.262
Authors: Frank M Brunkhorst; Christoph Engel; Max Ragaller; Tobias Welte; Rolf Rossaint; Herwig Gerlach; Konstantin Mayer; Stefan John; Frank Stuber; Norbert Weiler; Michael Oppert; Onnen Moerer; Holger Bogatsch; Konrad Reinhart; Markus Loeffler; Christiane Hartog Journal: Crit Care Med Date: 2008-10 Impact factor: 7.598