Literature DB >> 25867939

The use of negative pressure wound therapy with an automated, volumetric fluid administration: an advancement in wound care.

Tom Wolvos1.   

Abstract

UNLABELLED: Introduction. This small pilot study introduces initial clinical experience with a system combining negative pressure wound therapy and negative pressure wound therapy with instillation (NPWT/NPWTi, V.A.C. ULTA™ Negative Pressure Wound Therapy, KCI USA, Inc, San Antonio, TX).
MATERIALS AND METHODS: The NPWT system with instillation delivers controlled volumetric fluid instillation, and uses instillation- specific reticulated open-cell foam (ROCF) dressings: Dressing A (ROCF-V, V.A.C. VeraFlo™ Dressing, KCI USA, Inc, San Antonio, TX) or Dressing B (ROCF-VC, V.A.C. VeraFlo Cleanse™ Dressing, KCI USA, Inc, San Antonio, TX). Six patients ranging in age from 26-83 years were treated with either NPWT with instillation and Dressing A or Dressing B, and Microcyn® antiseptic solution (Oculus Innovative Sciences, Petaluma, CA) (n = 5) or quarter- strength Dakin's Solution® (Century Pharmaceuticals, Indianapolis, IN) (n = 1), as the instillate. Negative pressure wound therapy was applied in 1 patient to a single wound using Dressing C (ROCF; V.A.C.® GranuFoam™ Dressing, KCI USA, Inc, San Antonio, TX) in one half of the wound, and Dressing B in the other half. In this patient series, instillation was repeated every 2-4 hours with a 5-10 minute soak time followed by negative pressure at -100 mm Hg to -125 mm Hg. All wounds were closed by skin graft or primary, secondary, or delayed primary intention.
RESULTS: For the wound treated with NPWT only, no difference in degree or quality of granulation tissue formation was observed by either dressing.
CONCLUSION: The system worked well across multiple wound types in either NPWT mode or NPWT with instillation mode, and no complications were observed. Larger patient studies with controls are needed to validate the clinical observations in this patient series. .

Entities:  

Year:  2013        PMID: 25867939

Source DB:  PubMed          Journal:  Wounds        ISSN: 1044-7946            Impact factor:   1.546


  9 in total

Review 1.  Diabetic foot wounds: the value of negative pressure wound therapy with instillation.

Authors:  Luca Dalla Paola
Journal:  Int Wound J       Date:  2013-12       Impact factor: 3.315

2.  Genomic and proteomic evaluation of tissue quality of porcine wounds treated with negative pressure wound therapy in continuous, noncontinuous, and instillation modes.

Authors:  Kathleen L Derrick; M Christian Lessing
Journal:  Eplasty       Date:  2014-12-04

3.  Intermittent negative pressure wound therapy with instillation for the treatment of persistent periprosthetic hip infections: a report of two cases.

Authors:  Mehmet Salih Söylemez; Korhan Özkan; Bülent Kılıç; Samet Erinç
Journal:  Ther Clin Risk Manag       Date:  2016-02-10       Impact factor: 2.423

4.  Temporary Abdominal Closure Combined With an Irrigating System Utilizing Hypochlorous Acid Solution to Decrease Abdominal Mucopurulence.

Authors:  Marc R Matthews; Asia N Quan; Alexandra S Weir; Kevin N Foster; Daniel M Caruso
Journal:  Eplasty       Date:  2018-02-26

5.  First Middle East Experience with Novel Foam Dressing Together with Negative Pressure Wound Therapy and Instillation.

Authors:  Muneera E Ben-Nakhi; Hazem I Eltayeb
Journal:  Cureus       Date:  2018-10-05

Review 6.  Clinical recommendations and practical guide for negative pressure wound therapy with instillation.

Authors:  Subhas Gupta; Allen Gabriel; John Lantis; Luc Téot
Journal:  Int Wound J       Date:  2015-05-23       Impact factor: 3.315

Review 7.  Novel foam dressing using negative pressure wound therapy with instillation to remove thick exudate.

Authors:  Luc Téot; Florian Boissiere; Sergiu Fluieraru
Journal:  Int Wound J       Date:  2017-02-28       Impact factor: 3.315

8.  Comparison of the Effects of Different Negative Pressure Wound Therapy Modes-Continuous, Noncontinuous, and With Instillation-on Porcine Excisional Wounds.

Authors:  M Christian Lessing; Roberta B James; Shannon C Ingram
Journal:  Eplasty       Date:  2013-10-01

9.  Use of negative pressure wound therapy in a chronic leg wound with coexisting rheumatoid arthritis: a case study.

Authors:  Dariusz Bazaliński; Paweł Więch; Beata Barańska; Monika Binkowska-Bury
Journal:  J Int Med Res       Date:  2018-05-13       Impact factor: 1.671

  9 in total

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