Literature DB >> 25865467

Estimating the costs of the vaccine supply chain and service delivery for selected districts in Kenya and Tanzania.

Mercy Mvundura1, Kristina Lorenson2, Amos Chweya3, Rosemary Kigadye4, Kathryn Bartholomew2, Mohammed Makame5, T Patrick Lennon2, Steven Mwangi6, Lydia Kirika6, Peter Kamau6, Abner Otieno6, Peninah Murunga3, Tom Omurwa3, Lyimo Dafrossa7, Debra Kristensen2.   

Abstract

Having data on the costs of the immunization system can provide decision-makers with information to benchmark the costs when evaluating the impact of new technologies or programmatic innovations. This paper estimated the supply chain and immunization service delivery costs and cost per dose in selected districts in Kenya and Tanzania. We also present operational data describing the supply chain and service delivery points (SDPs). To estimate the supply chain costs, we collected resource-use data for the cold chain, distribution system, and health worker time and per diems paid. We also estimated the service delivery costs, which included the time cost of health workers to provide immunization services, and per diems and transport costs for outreach sessions. Data on the annual quantities of vaccines distributed to each facility, and the occurrence and duration of stockouts were collected from stock registers. These data were collected from the national store, 2 regional and 4 district stores, and 12 SDPs in each country for 2012. Cost per dose for the supply chain and immunization service delivery were estimated. The average annual costs per dose at the SDPs were $0.34 (standard deviation (s.d.) $0.18) for Kenya when including only the vaccine supply chain costs, and $1.33 (s.d. $0.82) when including immunization service delivery costs. In Tanzania, these costs were $0.67 (s.d. $0.35) and $2.82 (s.d. $1.64), respectively. Both countries experienced vaccine stockouts in 2012, bacillus Calmette-Guérin vaccine being more likely to be stocked out in Kenya, and oral poliovirus vaccine in Tanzania. When stockouts happened, they usually lasted for at least one month. Tanzania made investments in 2011 in preparation for planned vaccine introductions, and their supply chain cost per dose is expected to decline with the new vaccine introductions. Immunization service delivery costs are a significant portion of the total costs at the SDPs.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cost per dose; Expanded Program on Immunization; Kenya; Micro-costing; Tanzania; Vaccine supply chain cost

Mesh:

Substances:

Year:  2015        PMID: 25865467     DOI: 10.1016/j.vaccine.2015.03.084

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  15 in total

1.  Presentation matters: Buffers, packaging, and delivery devices for new, oral enteric vaccines for infants.

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Journal:  Hum Vaccin Immunother       Date:  2017-01-02       Impact factor: 3.452

2.  Alternative vaccine administration by powder injection: Needle-free dermal delivery of the glycoconjugate meningococcal group Y vaccine.

Authors:  Nikolas T Weissmueller; Leanne Marsay; Heiko A Schiffter; Robert C Carlisle; Christine S Rollier; Robert K Prud'homme; Andrew J Pollard
Journal:  PLoS One       Date:  2017-08-24       Impact factor: 3.240

3.  Cost-effectiveness analysis of typhoid conjugate vaccines in five endemic low- and middle-income settings.

Authors:  Marina Antillón; Joke Bilcke; A David Paltiel; Virginia E Pitzer
Journal:  Vaccine       Date:  2017-05-17       Impact factor: 3.641

4.  Cost of goods sold and total cost of delivery for oral and parenteral vaccine packaging formats.

Authors:  Jeff Sedita; Stefanie Perrella; Matt Morio; Michael Berbari; Jui-Shan Hsu; Eugene Saxon; Courtney Jarrahian; Annie Rein-Weston; Darin Zehrung
Journal:  Vaccine       Date:  2018-02-12       Impact factor: 3.641

5.  Sustaining pneumococcal vaccination after transitioning from Gavi support: a modelling and cost-effectiveness study in Kenya.

Authors:  John Ojal; Ulla Griffiths; Laura L Hammitt; Ifedayo Adetifa; Donald Akech; Collins Tabu; J Anthony G Scott; Stefan Flasche
Journal:  Lancet Glob Health       Date:  2019-05       Impact factor: 26.763

6.  Potency of a thermostabilised chimpanzee adenovirus Rift Valley Fever vaccine in cattle.

Authors:  Pawan Dulal; Daniel Wright; Rebecca Ashfield; Adrian V S Hill; Bryan Charleston; George M Warimwe
Journal:  Vaccine       Date:  2016-03-25       Impact factor: 3.641

7.  Experiences of operational costs of HPV vaccine delivery strategies in Gavi-supported demonstration projects.

Authors:  Siobhan Botwright; Taylor Holroyd; Shreya Nanda; Paul Bloem; Ulla K Griffiths; Anissa Sidibe; Raymond C W Hutubessy
Journal:  PLoS One       Date:  2017-10-10       Impact factor: 3.240

8.  Evaluating the cost per child vaccinated with full versus fractional-dose inactivated poliovirus vaccine.

Authors:  Mercy Mvundura; Jui-Shan Hsu; Collrane Frivold; Debra Kristensen; Shanda Boyle; Darin Zehrung; Courtney Jarrahian
Journal:  Vaccine X       Date:  2019-07-15

Review 9.  A Systematic Review of the Incremental Costs of Implementing a New Vaccine in the Expanded Program of Immunization in Sub-Saharan Africa.

Authors:  Joe Brew; Christophe Sauboin
Journal:  MDM Policy Pract       Date:  2019-12-19

10.  Seasonal influenza vaccination in Kenya: an economic evaluation using dynamic transmission modelling.

Authors:  Jeanette Dawa; Gideon O Emukule; Edwine Barasa; Marc Alain Widdowson; Omu Anzala; Edwin van Leeuwen; Marc Baguelin; Sandra S Chaves; Rosalind M Eggo
Journal:  BMC Med       Date:  2020-08-20       Impact factor: 8.775

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