Literature DB >> 25864658

Where do injectable stem cell treatments apply in treatment of muscle, tendon, and ligament injuries?

Kenneth Mautner1, Joseph Blazuk1.   

Abstract

Treatment options for muscle, tendon, and ligament injuries span a constantly evolving spectrum. For years, treatments focused on symptomatic relief. Closer scrutiny of symptomatic treatment suggests that the provision of transient relief of symptoms may have caused more harm than good. Cortisone injections provide a trade-off of short-term relief for poorer long-term outcomes. When conventional treatment failed, patients have faced limited options including surgery, which has increased risk and limited efficacy. Regenerative injections offer a more robust option for soft tissue disease. Basic science and clinical studies show conflicting results to support the use of platelet-rich plasma injections for soft tissue disorders, and even fewer trials have focused on injectable stem cells with limited findings. Additional studies are needed to determine the potential benefits of this regenerative therapy.
Copyright © 2015 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2015        PMID: 25864658     DOI: 10.1016/j.pmrj.2014.12.012

Source DB:  PubMed          Journal:  PM R        ISSN: 1934-1482            Impact factor:   2.298


  2 in total

Review 1.  Nonoperative treatment of five common shoulder injuries: A critical analysis.

Authors:  Jonas Pogorzelski; Erik M Fritz; Jonathan A Godin; Andreas B Imhoff; Peter J Millett
Journal:  Obere Extrem       Date:  2018-02-19

2.  Differing efficacies of autologous platelet-rich plasma treatment in reducing pain following rotator-cuff injury in a single patient.

Authors:  Damien P Kuffler
Journal:  J Pain Res       Date:  2018-10-09       Impact factor: 3.133

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.