Literature DB >> 25862931

The molecular basis for the substrate specificity of protein tyrosine phosphatase PTPN3.

Emily J Parker1.   

Abstract

In this issue of Structure, Chen et al. present structures of the FERM-containing protein tyrosine phosphatase PTPN3 in complex with a phosphopeptide fragment of substrate epidermal growth factor receptor pathway substrate, providing detailed information on substrate specificity.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID: 25862931     DOI: 10.1016/j.str.2015.03.005

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  3 in total

1.  PTPN3 acts as a tumor suppressor and boosts TGF-β signaling independent of its phosphatase activity.

Authors:  Bo Yuan; Jinquan Liu; Jin Cao; Yi Yu; Hanchenxi Zhang; Fei Wang; Yezhang Zhu; Mu Xiao; Sisi Liu; Youqiong Ye; Le Ma; Dewei Xu; Ningyi Xu; Yi Li; Bin Zhao; Pinglong Xu; Jianping Jin; Jianming Xu; Xi Chen; Li Shen; Xia Lin; Xin-Hua Feng
Journal:  EMBO J       Date:  2019-06-14       Impact factor: 11.598

2.  Protein tyrosine phosphatase PTPN3 promotes drug resistance and stem cell-like characteristics in ovarian cancer.

Authors:  Shuqin Li; Jian Cao; Wei Zhang; Fan Zhang; Guantai Ni; Qian Luo; Man Wang; Xiang Tao; Hongping Xia
Journal:  Sci Rep       Date:  2016-11-11       Impact factor: 4.379

3.  Exome and copy number variation analyses of Mayer-Rokitansky-Küster- Hauser syndrome.

Authors:  Kazumi Takahashi; Takahide Hayano; Ryota Sugimoto; Hirofumi Kashiwagi; Mari Shinoda; Yoshihiro Nishijima; Takahiro Suzuki; Shingo Suzuki; Yuko Ohnuki; Akane Kondo; Takashi Shiina; Hirofumi Nakaoka; Ituro Inoue; Shun-Ichiro Izumi
Journal:  Hum Genome Var       Date:  2018-09-27
  3 in total

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