Literature DB >> 25861769

Visuo-constructional functions in patients with mild cognitive impairment, Alzheimer's disease, and Parkinson's disease.

Johann Lehrner1, Harald Krakhofer2, Claus Lamm2, Stefan Macher3, Doris Moser3, Stefanie Klug3, Peter Dal-Bianco3, Walter Pirker3, Eduard Auff3, Gisela Pusswald3.   

Abstract

BACKGROUND: Several recently proposed criteria for assessing cognitive disorder require measuring the cognitive domain of visuo-constructional function. The aims of the present study were to develop a new test (Vienna Visuo-constructional Test-VVT) measuring visuo-constructional functions and to determine the reliability and validity of the VVT in patients with mild cognitive impairment (MCI), Parkinson's disease (PD), and Alzheimer's disease (AD). We further examined age and sex effects and the psychometric quality of the VVT.
METHODS: The study included 76 healthy controls and 103 patients who were referred to the Department of Neurology, Medical University of Vienna for neurocognitive assessment. An administering and scoring system for the VVT was developed.
RESULTS: Internal consistency (Cronbach's alpha) was found to range from 0.82 for the healthy control group to 0.93 for the total patient group. There was no sex effect, but age had a negative effect on VVT performance. The VVT successfully differentiated healthy controls from MCI patients, AD patients, and PD patients, respectively.
CONCLUSION: The VVT shows satisfactory validity and reliability and can be administered easily in clinical practice. It constitutes a new measure that can successfully be used to identify visuo-constructional problems in patients with cognitive dysfunction.

Entities:  

Keywords:  Alzheimer’s disease; Mild cognitive impairment (MCI); Parkinson’s disease; Visuo-constructional function

Mesh:

Year:  2015        PMID: 25861769     DOI: 10.1007/s40211-015-0141-2

Source DB:  PubMed          Journal:  Neuropsychiatr        ISSN: 0948-6259


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