Literature DB >> 25861611

Prophylactic antibiotic administration for post cardiothoracic surgery sternal wounds: a retrospective study.

Georgia Pitsiou1, Ioannis Kioumis1, Konstantinos Zarogoulidis1, George Lazaridis1, Antonis Papaiwannou1, Katerina Tsirgogianni1, Anastasia Karavergou1, Sofia Lampaki1, Aggeliki Rapti1, Georgia Trakada1, Athanasios Zissimopoulos1, Theodoros Karaiskos1, Athanasios Madesis1, Georgios Drosos1, Paul Zarogoulidis1.   

Abstract

BACKGROUND: Cardiothoracic surgery sternal infections are difficult to treat situations. Until now there are no clear guidelines which or if an antibiotic could be used as prophylactic treatment. PATIENTS AND METHODS: We collected retrospectively data from 535 patients from our hospital which underwent cardiothoracic surgery and recorded several biological parameters and technical aspects of the surgery.
RESULTS: It was observed that patients to whom vancomycin was administered had less post surgery infection than those to whom begalin was administered. Male who were treated with vancomycin it was observed that they had 1.67 chances to be treated properly than female. Patients which were hospitalized for more than 7 days before surgery had 62.6% higher chances for post surgery infection.
CONCLUSIONS: It was observed that vancomycin can be used as a prophylactic treatment for cardiothoracic surgeries acting efficiently against sternal wounds.

Entities:  

Keywords:  Vancomycin; infection; sultamicilin; surgery

Year:  2015        PMID: 25861611      PMCID: PMC4381471          DOI: 10.3978/j.issn.2305-5839.2015.03.22

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


  40 in total

1.  Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients.

Authors:  F Roques; S A Nashef; P Michel; E Gauducheau; C de Vincentiis; E Baudet; J Cortina; M David; A Faichney; F Gabrielle; E Gams; A Harjula; M T Jones; P P Pintor; R Salamon; L Thulin
Journal:  Eur J Cardiothorac Surg       Date:  1999-06       Impact factor: 4.191

Review 2.  Avoparcin and virginiamycin as animal growth promoters: a plea for science in decision-making.

Authors:  J Acar; M Casewell; J Freeman; C Friis; H Goossens
Journal:  Clin Microbiol Infect       Date:  2000-09       Impact factor: 8.067

3.  Vancomycin: a 50-year reassessment.

Authors:  Robert C Moellering
Journal:  Clin Infect Dis       Date:  2006-01-01       Impact factor: 9.079

Review 4.  Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists.

Authors:  Michael Rybak; Ben Lomaestro; John C Rotschafer; Robert Moellering; William Craig; Marianne Billeter; Joseph R Dalovisio; Donald P Levine
Journal:  Am J Health Syst Pharm       Date:  2009-01-01       Impact factor: 2.637

5.  Vancomycin susceptibility as an aid to the identification of lactobacilli.

Authors:  J M Hamilton-Miller; S Shah
Journal:  Lett Appl Microbiol       Date:  1998-02       Impact factor: 2.858

6.  Hospitalization before surgery increases risk for postoperative infections.

Authors:  Marta Kelava; Michael Robich; Penny L Houghtaling; Joseph F Sabik; Steven Gordon; Tomislav Mihaljevic; Eugene H Blackstone; Colleen G Koch
Journal:  J Thorac Cardiovasc Surg       Date:  2014-07-21       Impact factor: 5.209

7.  Avoparcin used as a growth promoter is associated with the occurrence of vancomycin-resistant Enterococcus faecium on Danish poultry and pig farms.

Authors:  F Bager; M Madsen; J Christensen; F M Aarestrup
Journal:  Prev Vet Med       Date:  1997-07       Impact factor: 2.670

8.  Changing glucose control target and risk of surgical site infection in a Southeast Asian population.

Authors:  Roderica Rui Ge Ng; Aung Myat Oo; Weiling Liu; Teing Ee Tan; Lian Kah Ti; Sophia Tsong Huey Chew
Journal:  J Thorac Cardiovasc Surg       Date:  2014-09-17       Impact factor: 5.209

9.  Mechanism of intrinsic resistance to vancomycin in Clostridium innocuum NCIB 10674.

Authors:  Véronique David; Bülent Bozdogan; Jean-Luc Mainardi; Raymond Legrand; Laurent Gutmann; Roland Leclercq
Journal:  J Bacteriol       Date:  2004-06       Impact factor: 3.490

10.  Vancomycin therapy for infective endocarditis.

Authors:  J E Geraci; W R Wilson
Journal:  Rev Infect Dis       Date:  1981 Nov-Dec
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