| Literature DB >> 25861030 |
Rumi Taniguchi1, Shin Koyano, Tatsuo Suzutani, Keiji Goishi, Yushi Ito, Ichiro Morioka, Hiroyuki Nakamura, Hideto Yamada, Akira Oka, Naoki Inoue.
Abstract
The potential risk factors for congenital cytomegalovirus (cCMV) infection or development of disease remain unclear. Here, we investigated the genetic polymorphisms in natural killer (NK) group 2, member D (NKG2D), an activating receptor expressed on NK cells, and in MHC class I-related chains A, the ligand of NKG2D, in 87 cCMV cases, and found that there was a significant association between cCMV disease and a single nucleotide polymorphism, Thr72Ala, in NKG2D.Entities:
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Year: 2015 PMID: 25861030 DOI: 10.1007/s15010-015-0774-x
Source DB: PubMed Journal: Infection ISSN: 0300-8126 Impact factor: 3.553