Literature DB >> 25860635

Correction: recurrent evolution of melanism in South American Felids.

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Abstract

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Year:  2015        PMID: 25860635      PMCID: PMC4393314          DOI: 10.1371/journal.pgen.1005126

Source DB:  PubMed          Journal:  PLoS Genet        ISSN: 1553-7390            Impact factor:   5.917


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Due to an error in the production process, the labels for panel D in Fig. 1 are misaligned. The correct figure is provided here.
Fig 1

Melanism mutations and phenotypes in three Leopardus species.

(A) Color phenotypes of the pampas cat (L. colocolo), Geoffroy’s cat (L. geoffroyi), and kodkod (L. guigna). Tabby markings in the non-melanistic (NM) forms shown here are obscured in the melanistic (M) forms. (B) Geographic distribution (modified from [7]); red circles represent the approximate origin of samples as described in the text. Right upper panel indicates phylogenetic relationships and estimated divergence times based on [4] (C, D) Location of missense variants in ASIP (kodkod, pampas cat) and MC1R (Geoffroy’s cat). (C) The kodkod and pampas cat variants are predicted to disrupt the three dimensional structure of a disulfide-stabilized loop in ASIP that is critical for MC1R binding [30]. (D) The Geoffroy’s cat melanism allele carries three missense variants in MC1R; C125R is likely to be causative as described in the text.

The Dryad DOI in the Data Availability Statement links out incorrectly. The correct Dryad link is http://dx.doi.org/10.5061/dryad.pq482.

Melanism mutations and phenotypes in three Leopardus species.

(A) Color phenotypes of the pampas cat (L. colocolo), Geoffroy’s cat (L. geoffroyi), and kodkod (L. guigna). Tabby markings in the non-melanistic (NM) forms shown here are obscured in the melanistic (M) forms. (B) Geographic distribution (modified from [7]); red circles represent the approximate origin of samples as described in the text. Right upper panel indicates phylogenetic relationships and estimated divergence times based on [4] (C, D) Location of missense variants in ASIP (kodkod, pampas cat) and MC1R (Geoffroy’s cat). (C) The kodkod and pampas cat variants are predicted to disrupt the three dimensional structure of a disulfide-stabilized loop in ASIP that is critical for MC1R binding [30]. (D) The Geoffroy’s cat melanism allele carries three missense variants in MC1R; C125R is likely to be causative as described in the text.
  1 in total

1.  Recurrent evolution of melanism in South American felids.

Authors:  Alexsandra Schneider; Corneliu Henegar; Kenneth Day; Devin Absher; Constanza Napolitano; Leandro Silveira; Victor A David; Stephen J O'Brien; Marilyn Menotti-Raymond; Gregory S Barsh; Eduardo Eizirik
Journal:  PLoS Genet       Date:  2015-02-19       Impact factor: 5.917

  1 in total

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