| Literature DB >> 25860383 |
Yanqun Song1, Maiyun Yang1, Seraphine V Wegner1,2, Jingyi Zhao3, Rongfeng Zhu4, Yun Wu5, Chuan He1,2,6, Peng R Chen1,4,6.
Abstract
Heme plays pivotal roles in various cellular processes as well as in iron homeostasis in living systems. Here, we report a genetically encoded fluorescence resonance energy transfer (FRET) sensor for selective heme imaging by employing a pair of bacterial heme transfer chaperones as the sensory components. This heme-specific probe allows spatial-temporal visualization of intracellular heme distribution within living cells.Entities:
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Year: 2015 PMID： 25860383 DOI： 10.1021/cb5009734
Source DB: PubMed Journal: ACS Chem Biol ISSN： 1554-8929 Impact factor: 5.100