The type B aortic dissection treatment is showing a paradigm change with the
consolidation of the endovascular treatment. Duarte et al.[ present a review of the most
important works that demonstrate this evolution. The concept that the type B aortic
dissection treatment is primarily clinical, with surgery reserved for complicated cases,
are based on the first publications of IRAD[, in 20001. This work showed hospital mortality of 10% for
clinically treated cases. The surgical treatment presented mortality rate of 31% with
18% of paraplegia. These results were not obtained by randomized controlled trials, nor
considered the technical innovations of the elephant's trunk and cerebral anterograde
perfusion. However, the patients initially treated medically, showed 20 to 50% of
mortality[ in late
evolution, providing the search for new treatments. The INSTEAD TRIAL[ was the first randomized multicenter
study comparing the optimized medical treatment with endovascular treatment in
uncomplicated type B aortic dissections in sub acute phase (15 to 30 days of evolution)
and chronic (more than 30 days of evolution). This study showed that, after three years
follow up, the endovascular treatment had lower mortality than medical treatment and
greater aortic remodeling and minor complications related to the aorta. There is'nt
scientific evidence, about the best treatment for cases of uncomplicated type B aortic
dissection in acute phase (less than or equal to 14 days of evolution). Recently, the
one year ADSORB TRIAL[
results were publishing. This work randomized the cases of uncomplicated type B aortic
dissection in acute phase to optimal medical treatment and endovascular treatment +
optimized medical treatment. Both groups showed no hospital mortality. The endovascular
treatment group had higher aortic remodeling, with increased in the true lumen diameter,
decrease the false lumen and aortic transverse diameter in one year follow up. This
study, despite the small sample, brings new information and concepts. The hospital
mortality was zero, lower than that of 10% presented by IRAD[, moreover, equalized the medical
treatment results with the medical treatment associated with endovascular treatment,
presented the latter positive bias after 1 year for aortic remodeling in the last group.
Long-term results will be needed to consolidate the concept that the early closure of
the false lumen is really independent factor for better performance and lower mortality
and higher aortic remodeling, as affirmed INSTEAD TRIAL[ and Akutsu et al.[.
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Authors: João Jackson Duarte; José Carlos Dorsa Vieira Pontes; Ricardo Adala Benfatti; Adriana Lugo Ferrachini; Walter Kegham Karakhanian; Alvaro Razuk Filho Journal: Rev Bras Cir Cardiovasc Date: 2014 Jul-Sep
Authors: J I Fann; J A Smith; D C Miller; R S Mitchell; K A Moore; G Grunkemeier; E B Stinson; P E Oyer; B A Reitz; N E Shumway Journal: Circulation Date: 1995-11-01 Impact factor: 29.690