Literature DB >> 25859877

Is clinical treatment the gold standard in the treatment of acute type B aortic dissections?

João Jackson Duarte1.   

Abstract

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Year:  2015        PMID: 25859877      PMCID: PMC4389515          DOI: 10.5935/1678-9741.20150002

Source DB:  PubMed          Journal:  Rev Bras Cir Cardiovasc


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The type B aortic dissection treatment is showing a paradigm change with the consolidation of the endovascular treatment. Duarte et al.[ present a review of the most important works that demonstrate this evolution. The concept that the type B aortic dissection treatment is primarily clinical, with surgery reserved for complicated cases, are based on the first publications of IRAD[, in 20001. This work showed hospital mortality of 10% for clinically treated cases. The surgical treatment presented mortality rate of 31% with 18% of paraplegia. These results were not obtained by randomized controlled trials, nor considered the technical innovations of the elephant's trunk and cerebral anterograde perfusion. However, the patients initially treated medically, showed 20 to 50% of mortality[ in late evolution, providing the search for new treatments. The INSTEAD TRIAL[ was the first randomized multicenter study comparing the optimized medical treatment with endovascular treatment in uncomplicated type B aortic dissections in sub acute phase (15 to 30 days of evolution) and chronic (more than 30 days of evolution). This study showed that, after three years follow up, the endovascular treatment had lower mortality than medical treatment and greater aortic remodeling and minor complications related to the aorta. There is'nt scientific evidence, about the best treatment for cases of uncomplicated type B aortic dissection in acute phase (less than or equal to 14 days of evolution). Recently, the one year ADSORB TRIAL[ results were publishing. This work randomized the cases of uncomplicated type B aortic dissection in acute phase to optimal medical treatment and endovascular treatment + optimized medical treatment. Both groups showed no hospital mortality. The endovascular treatment group had higher aortic remodeling, with increased in the true lumen diameter, decrease the false lumen and aortic transverse diameter in one year follow up. This study, despite the small sample, brings new information and concepts. The hospital mortality was zero, lower than that of 10% presented by IRAD[, moreover, equalized the medical treatment results with the medical treatment associated with endovascular treatment, presented the latter positive bias after 1 year for aortic remodeling in the last group. Long-term results will be needed to consolidate the concept that the early closure of the false lumen is really independent factor for better performance and lower mortality and higher aortic remodeling, as affirmed INSTEAD TRIAL[ and Akutsu et al.[.
  6 in total

1.  Effects of the patent false lumen on the long-term outcome of type B acute aortic dissection.

Authors:  Koichi Akutsu; Jun Nejima; Kaname Kiuchi; Kenji Sasaki; Masami Ochi; Keiji Tanaka; Teruo Takano
Journal:  Eur J Cardiothorac Surg       Date:  2004-08       Impact factor: 4.191

2.  Endovascular repair of type B aortic dissection: long-term results of the randomized investigation of stent grafts in aortic dissection trial.

Authors:  Christoph A Nienaber; Stephan Kische; Hervé Rousseau; Holger Eggebrecht; Tim C Rehders; Guenther Kundt; Aenne Glass; Dierk Scheinert; Martin Czerny; Tilo Kleinfeldt; Burkhart Zipfel; Louis Labrousse; Rossella Fattori; Hüseyin Ince
Journal:  Circ Cardiovasc Interv       Date:  2013-08-06       Impact factor: 6.546

3.  The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease.

Authors:  P G Hagan; C A Nienaber; E M Isselbacher; D Bruckman; D J Karavite; P L Russman; A Evangelista; R Fattori; T Suzuki; J K Oh; A G Moore; J F Malouf; L A Pape; C Gaca; U Sechtem; S Lenferink; H J Deutsch; H Diedrichs; J Marcos y Robles; A Llovet; D Gilon; S K Das; W F Armstrong; G M Deeb; K A Eagle
Journal:  JAMA       Date:  2000-02-16       Impact factor: 56.272

4.  Endovascular repair of acute uncomplicated aortic type B dissection promotes aortic remodelling: 1 year results of the ADSORB trial.

Authors:  J Brunkwall; P Kasprzak; E Verhoeven; R Heijmen; P Taylor; P Alric; L Canaud; M Janotta; D Raithel; W Malina; Ti Resch; H-H Eckstein; S Ockert; T Larzon; F Carlsson; H Schumacher; S Classen; P Schaub; J Lammer; L Lönn; R E Clough; V Rampoldi; S Trimarchi; J-N Fabiani; D Böckler; D Kotelis; D Böckler; D Kotelis; H von Tenng-Kobligk; N Mangialardi; S Ronchey; G Dialetto; V Matoussevitch
Journal:  Eur J Vasc Endovasc Surg       Date:  2014-06-22       Impact factor: 7.069

Review 5.  Indication of endovascular treatment of type B aortic dissection--literature review.

Authors:  João Jackson Duarte; José Carlos Dorsa Vieira Pontes; Ricardo Adala Benfatti; Adriana Lugo Ferrachini; Walter Kegham Karakhanian; Alvaro Razuk Filho
Journal:  Rev Bras Cir Cardiovasc       Date:  2014 Jul-Sep

6.  Surgical management of aortic dissection during a 30-year period.

Authors:  J I Fann; J A Smith; D C Miller; R S Mitchell; K A Moore; G Grunkemeier; E B Stinson; P E Oyer; B A Reitz; N E Shumway
Journal:  Circulation       Date:  1995-11-01       Impact factor: 29.690

  6 in total

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