| Literature DB >> 25859599 |
E G Sukhorukova, D É Kruzhevskiĭ, O S Alekseeva.
Abstract
Glial fibrillary acidic protein (GFAP) refers to the type III intermediate filament proteins and is the essential component of the cytoskeleton in astrocytes of all vertebrates. This review presents current data on the molecular organization of GFAP in a comparative aspect. The results of most relevant studies using immunocytochemical labeling of the protein are summarized. The data on the changes in expression of GFAP in Alexander disease caused by the primary pathology of astrocytes are presented.Entities:
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Year: 2015 PMID： 25859599
Source DB: PubMed Journal: Zh Evol Biokhim Fiziol ISSN： 0044-4529