Literature DB >> 25859482

Cirrhosis: an unusual presentation of sickle cell disease.

Rupal Dosi1, Rushad Patell2, Pooja Jariwala3, Purav Shah4, Sarfaraz Jasdanwala5.   

Abstract

Hepatobiliary complications of sickle cell disease are relatively rare but well recognised in literature. Clinical syndromes range from mild intrahepatic cholestasis and gallstones to life threatening sequestration crisis. Most patients, homozygous for sickle cell anaemia, present before adolescence. We report a case of an adult man with no prior symptoms who presented for the first time with decompensated cirrhosis, which was found to be due to underlying previously unrecognised sickle cell anaemia.

Entities:  

Keywords:  Cirrhosis; Sickle cell disease; Sickle cell hepatopathy

Year:  2015        PMID: 25859482      PMCID: PMC4378764          DOI: 10.7860/JCDR/2015/8572.5501

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  7 in total

Review 1.  Sickle cell hepatopathy.

Authors:  S Banerjee; C Owen; S Chopra
Journal:  Hepatology       Date:  2001-05       Impact factor: 17.425

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Authors:  T W GREEN; C L CONLEY; M BERTHRONG
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Authors:  Parijat Gupte; Aabha Nagral
Journal:  Trop Gastroenterol       Date:  2009 Apr-Jun

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Authors:  T T Schubert
Journal:  Gastroenterology       Date:  1986-06       Impact factor: 22.682

6.  Hepatic dysfunction in sickle cell disease: a new system of classification based on global assessment.

Authors:  Philip A Berry; Timothy J S Cross; Swee Lay Thein; Bernard C Portmann; Julia A Wendon; John B Karani; Michael A Heneghan; Adrian Bomford
Journal:  Clin Gastroenterol Hepatol       Date:  2007-09-27       Impact factor: 11.382

7.  Acute sickle cell hepatopathy represents a potential contraindication for percutaneous liver biopsy.

Authors:  Nada Zakaria; Alex Knisely; Bernard Portmann; Giorgina Mieli-Vergani; Julia Wendon; Roopen Arya; John Devlin
Journal:  Blood       Date:  2002-08-15       Impact factor: 22.113

  7 in total

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