Mousumi Malakar1, Syed Nasir Askari2, Humayun Ashraf2, Abdul Waris3, Anupam Ahuja4, Adil Asghar5. 1. Junior Resident, Department of Ophthalmology, JN Medical College , Aligarh, U.P., India . 2. Professor, Department of Ophthalmology, JN Medical College , Aligarh, U.P., India . 3. Assistant Professor, Department of Ophthalmology, JN Medical College , Aligarh, U.P., India . 4. Medical Director, Gandhi Eye Hospital , Aligarh, U.P., India . 5. Assistant Professor, Department of Anatomy, HIMSR, Jamia Hamdard , New Delhi, India .
Abstract
INTRODUCTION: To evaluate the association of high myopia with retinal nerve fibre layer (RNFL) thickness by Fourier domain optical coherence tomography (FD OCT). MATERIALS AND METHODS: Fifty highly myopic eyes (25 patients) and forty emmetropic eyes (20 Normal subject) were randomly selected after excluding concomitant ophthalmic disorder and RNFL thickness measured using the Fourier domain optical coherence tomography (FD OCT). RESULTS: The overall mean RNFL thickness in the myopic groups and control were 87.89 μm and 111.64 μm respectively. The mean retinal nerve fibre thickness was significantly less in myopic eyes as compared to control group (p =0.0001). Retinal nerve fibre layer thickness shows topographic double hump pattern in both the groups (myopes and emmetropes). CONCLUSION: Retinal nerve fibre thickness was significantly less in myopic eyes as compared to emmetropic eyes. The retinal nerve fibre layer thinning in high myopes may be confused with open angle glaucoma, a disease also prevalent in high myopes. There is therefore a need to have retinal nerve fibre layer thickness normogram for high myopes of a given population group to avoid wrong interpretation.
INTRODUCTION: To evaluate the association of high myopia with retinal nerve fibre layer (RNFL) thickness by Fourier domain optical coherence tomography (FD OCT). MATERIALS AND METHODS: Fifty highly myopic eyes (25 patients) and forty emmetropic eyes (20 Normal subject) were randomly selected after excluding concomitant ophthalmic disorder and RNFL thickness measured using the Fourier domain optical coherence tomography (FD OCT). RESULTS: The overall mean RNFL thickness in the myopic groups and control were 87.89 μm and 111.64 μm respectively. The mean retinal nerve fibre thickness was significantly less in myopic eyes as compared to control group (p =0.0001). Retinal nerve fibre layer thickness shows topographic double hump pattern in both the groups (myopes and emmetropes). CONCLUSION: Retinal nerve fibre thickness was significantly less in myopic eyes as compared to emmetropic eyes. The retinal nerve fibre layer thinning in high myopes may be confused with open angle glaucoma, a disease also prevalent in high myopes. There is therefore a need to have retinal nerve fibre layer thickness normogram for high myopes of a given population group to avoid wrong interpretation.
Authors: Sek-Tien Hoh; Marcus C C Lim; Steve K L Seah; Albert T H Lim; Sek-Jin Chew; Paul J Foster; Tin Aung Journal: Ophthalmology Date: 2006-05 Impact factor: 12.079
Authors: D Huang; E A Swanson; C P Lin; J S Schuman; W G Stinson; W Chang; M R Hee; T Flotte; K Gregory; C A Puliafito Journal: Science Date: 1991-11-22 Impact factor: 47.728
Authors: J S Schuman; M R Hee; C A Puliafito; C Wong; T Pedut-Kloizman; C P Lin; E Hertzmark; J A Izatt; E A Swanson; J G Fujimoto Journal: Arch Ophthalmol Date: 1995-05
Authors: Zane Z Zemborain; Ravivarn Jarukasetphon; Emmanouil Tsamis; Carlos G De Moraes; Robert Ritch; Donald C Hood Journal: J Glaucoma Date: 2020-10 Impact factor: 2.290