Literature DB >> 25858932

Not all secondary bone tumours are secondaries. Concurrent metastatic breast carcinoma and chondrosarcoma of the femur.

Preethy Nath1, Elizabeth Sankey1, Elisabeth Murray1, Harish Kurup1.   

Abstract

We present a case of metastatic adenocarcinoma of the breast in a patient who sustained a pathological fracture of the distal femur. Histology of the distal femur lesion excised at the time of endoprosthetic replacement confirmed this to be a primary chondrosarcoma. We have reviewed the literature and identified previously documented cases of concurrent breast carcinoma and chondrosarcoma of bone. A high index of suspicion is warranted and the diagnosis must be first confirmed before rushing to internal fixation (therapeutic or prophylactic) assuming them to be secondary bone lesions from the known primary cancer even in patients with multiple metastases. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 25858932      PMCID: PMC4401906          DOI: 10.1136/bcr-2014-208929

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

1.  [Breast carcinoma and bone chondrosarcoma: a new syndrome?].

Authors:  P Guedin; J Chasle; C Blanc-Fournier; J Lacroix
Journal:  J Radiol       Date:  2006-11

2.  A distinct phenotype characterizes tumors from a putative genetic trait involving chondrosarcoma and breast cancer occurring in the same patient.

Authors:  Anne-Marie Cleton-Jansen; Michel C Timmerman; Marc J van de Vijver; Christi J van Asperen; Herman M Kroon; Paul H C Eilers; Pancras C W Hogendoorn
Journal:  Lab Invest       Date:  2004-02       Impact factor: 5.662

Review 3.  Primary chondrosarcoma of the breast: a case presentation and review of the literature.

Authors:  Sanaa Errarhay; Mohamed Fetohi; Samia Mahmoud; Hanane Saadi; Chahrazed Bouchikhi; Abdelaziz Banani
Journal:  World J Surg Oncol       Date:  2013-08-21       Impact factor: 2.754

  3 in total

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