Literature DB >> 25858800

Genetic association analyses of neuregulin 1 gene polymorphism with endopheontype for sociality of Korean autism spectrum disorders family.

Hee Jeong Yoo1, Ran-Sook Woo2, Soo-Churl Cho3, Boong-Nyun Kim3, Jae-Won Kim3, Min-Sup Shin3, Tae-Won Park4, Jung-Woo Son5, Un-Sun Chung6, Subin Park3, Mira Park7, Soon Ae Kim8.   

Abstract

To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Autism spectrum disorder; Family-based association study; Neuregulin 1

Mesh：

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Year:  2015        PMID： 25858800     DOI： 10.1016/j.psychres.2015.03.015

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  3 in total

1.  Polymorphism in the Promoter Region of SEMA5A Is Associated with Sociality Traits in Korean Subjects with Autism Spectrum Disorders.

Authors:  Soon Ae Kim; Boong-Nyun Kim; Jae-Won Kim; Min-Sup Shin; Tae-Won Park; Jung-Woo Son; Un-Sun Chung; Mira Park
Journal:  Psychiatry Investig       Date:  2017-11-07       Impact factor: 2.505

2.  mGluR1-Dependent Long Term Depression in Rodent Midbrain Dopamine Neurons Is Regulated by Neuregulin 1/ErbB Signaling.

Authors:  Ada Ledonne; Nicola Biagio Mercuri
Journal:  Front Mol Neurosci       Date:  2018-10-01       Impact factor: 5.639

Review 3.  On the Modulatory Roles of Neuregulins/ErbB Signaling on Synaptic Plasticity.

Authors:  Ada Ledonne; Nicola B Mercuri
Journal:  Int J Mol Sci       Date:  2019-12-31       Impact factor: 5.923
  3 in total

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