Literature DB >> 25858623

Metal-free cascade cyclization of alkenes toward perfluorinated oxindoles.

Shi Tang1, Zhi-Hao Li, Ming-Wei Wang, Zhi-Ping Li, Rui-Long Sheng.   

Abstract

A simple AIBN-mediated cyclization reaction of activated alkenes toward perfluorinated oxindoles is developed. In the presence of readily available AIBN, N-arylacrylamide and perfluoroalkyl iodides underwent perfluorination reaction to give perfluorinated oxindoles in good to excellent yields under metal-free conditions.

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Year:  2015        PMID: 25858623     DOI: 10.1039/c5ob00454c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

1.  Synthesis of trifluoromethyl-containing isoindolinones from tertiary enamides via a cascade radical addition and cyclization process.

Authors:  Hui Yu; Mingdong Jiao; Xiaowei Fang; Pengfei Xuan
Journal:  RSC Adv       Date:  2018-07-03       Impact factor: 3.361

  1 in total

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