Literature DB >> 25858303

Ocular toxocariasis: new diagnostic and therapeutic perspectives.

Dayron F Martínez-Pulgarín, Marcela Muñoz-Urbano, Luz D Gomez-Suta, Olinda M Delgado, Alfonso J Rodriguez-Morales1.   

Abstract

PURPOSE: To provide an updated insight of concepts regarding the overview, epidemiology, risk factors, clinical manifestations, diagnosis, treatment and prevention of ocular toxocariasis.
DESIGN: Perspective of literature review.
METHODS: Review and synthesis of literature about toxocariasis, with interpretation and perspective. A literature search for "ocular toxocariasis" was performed using PubMed, ScienceDirect, Scopus, SciELO and LILACS databases.
RESULTS: Mild to moderate infections are frequently reported in ocular toxocariasis which usually occurs in children and typically presents as unilateral vision impairment, blindness is common and could present invasion of the retina. There are three groups of presentation of toxocariasis (according to the physical examination): chronic endophthalmitis, posterior granuloma and peripheral granuloma. Standard diagnosis of ocular toxocariasis is based on the identification of clinical signs, supported by additional diagnostic methods. Regarding treatment, there is no commonly accepted regimen but most of the authors prefer to use steroids and anthelminthic agents, but nowadays there are no standardized parameters in terms of dosage, duration and route of administration. Surgery has been recommended in some cases.
CONCLUSION: Toxocariasis is still a problem of public health, particularly in developing countries with an increasing epidemiological burden in terms of morbidity and mortality and most of the authors agree on the utmost relevance of its prevention. Clinical experience and suspicion of ophthalmologists make an important role in its diagnosis, but always with supportive diagnostic methods. Additional studies should explore new therapeutic options for toxocariasis.

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Year:  2015        PMID: 25858303     DOI: 10.2174/1574891x10666150410125057

Source DB:  PubMed          Journal:  Recent Pat Antiinfect Drug Discov        ISSN: 1574-891X


  8 in total

1.  Ocular toxocariasis: atypical clinical course.

Authors:  Cristina Fonseca; Andreia Mendes Silva; Sandra Freire; Rui Proença
Journal:  BMJ Case Rep       Date:  2019-04-04

2.  Unusual eye findings in a patient with atypical hemolytic uremic syndrome: Answers.

Authors:  Begüm Avcı; Şengül Özdek; İmren Akkoyun; Esra Baskın
Journal:  Pediatr Nephrol       Date:  2022-01-27       Impact factor: 3.651

3.  Toxocariasis of the eye.

Authors:  Zui Tao; Zhengqin Yin; Tongtao Zhao; Shiying Li
Journal:  IDCases       Date:  2017-06-10

4.  Toxocara Optic Disc Granuloma: Deep Range Imaging Optical Coherence Tomography Findings.

Authors:  Izabella Karska-Basta; Agnieszka Kubicka-Trząska; Michał Chrząszcz; Weronika Pociej-Marciak; Bożena Romanowska-Dixon
Journal:  Case Rep Ophthalmol       Date:  2019-10-16

5.  The Value of the Antibody Detection in the Diagnosis of Ocular Toxocariasis and the Aqueous Cytokine Profile Associated With the Condition.

Authors:  Xiang Zhang; Yuan Yang; Yan Zheng; Yiqian Hu; Yuqing Rao; Jiakai Li; Peiquan Zhao; Jing Li
Journal:  Front Med (Lausanne)       Date:  2022-03-28

6.  Ocular Toxocariasis Associated with Blurred Vision and Visual Impairment: Report of Four Cases.

Authors:  Mohammad Zibaei; Fatemeh Sadat Mahdavi; Farzaneh Firoozeh; Hamidreza Hasani; Saeed Bahadory
Journal:  Iran J Parasitol       Date:  2022 Jan-Mar       Impact factor: 1.217

Review 7.  Toxocariasis: a silent threat with a progressive public health impact.

Authors:  Jia Chen; Quan Liu; Guo-Hua Liu; Wen-Bin Zheng; Sung-Jong Hong; Hiromu Sugiyama; Xing-Quan Zhu; Hany M Elsheikha
Journal:  Infect Dis Poverty       Date:  2018-06-13       Impact factor: 4.520

8.  Low Toxocara Seroprevalence in People in Rural Durango, Mexico.

Authors:  Cosme Alvarado-Esquivel; Ángel Osvaldo Alvarado-Félix; Gustavo Alexis Alvarado-Félix
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2019-08-22
  8 in total

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