Literature DB >> 25857986

Complexation of synthetic CDM-AM copolymer with natamycin and carbendazim to improve solubility and fungicidal activity.

Yong-Fu Li1, Jing Jin1, Qin Guo1, Yi-Ming Ha2, Qing-Peng Li1.   

Abstract

The β-cyclodextrin-acrylamide (CDM-AM) copolymer was prepared from acrylamide and β-CD maleate (CDM) using K2S2O8 as initiator. The effects of the CDM-AM copolymer on the solubility and fungicidal activity of natamycin (NM) and carbendazim (MBC) were investigated. The stability constant of NM·CDM-AM and MBC·CDM-AM complexes at 303 K were of 10,725.45 M(-1) and 3000.89 M(-1), respectively. The complexes were characterized using phase solubility diagrams, NMR spectra and FT-IR spectra. The analysis of the biological activities of these two complexes indicated that they possessed enhancing fungicidal activities compared to NM and MBC alone.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Aspergillus niger; Carbendazim; Isothermal adsorption; Natamycin; Rheological properties; Solubility

Mesh:

Substances:

Year:  2015        PMID: 25857986     DOI: 10.1016/j.carbpol.2015.02.055

Source DB:  PubMed          Journal:  Carbohydr Polym        ISSN: 0144-8617            Impact factor:   9.381


  3 in total

1.  Development of Starch-Based Antifungal Coatings by Incorporation of Natamycin/Methyl-β-Cyclodextrin Inclusion Complex for Postharvest Treatments on Cherry Tomato against Botrytis cinerea.

Authors:  Yuexi Yang; Chen Huan; Xianrui Liang; Sheng Fang; Jian Wang; Jie Chen
Journal:  Molecules       Date:  2019-11-01       Impact factor: 4.411

2.  Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model.

Authors:  Zejiang Zhu; Jiaolin Wen; Yaohui Xu; Heying Pei; Dan Li; Minghai Tang; Peng Bai; Jun He; Zhuang Yang; Lijuan Chen
Journal:  Ann Med       Date:  2022-12       Impact factor: 4.709

3.  The synthesis of water-soluble CDM-AM copolymer by irradiation and its solubilization effect on hydrophobic drugs.

Authors:  Yong-Fu Li; Hong-Tao Tang; Si-Jing Zhou
Journal:  Des Monomers Polym       Date:  2018-06-25       Impact factor: 2.650

  3 in total

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