Literature DB >> 25856810

Brexpiprazole: another multipurpose antipsychotic drug?

Robert H Howland.   

Abstract

Brexpiprazole (also known as OPC-34712 or Lu-AF41156) is a novel molecular compound chemically and structurally similar to aripiprazole. This drug is currently under review by the U.S. Food and Drug Administration as a monotherapy for schizophrenia and an adjunct to antidepressant medication for major depressive disorder. Additional clinical trials include studies of brexpiprazole in attention-deficit/hyperactivity disorder and posttraumatic stress disorder, and for agitation associated with dementia of the Alzheimer's type. Brexpiprazole is an example that illustrates how pharmacological drug diversity may be translated to multipurpose uses. Copyright 2015, SLACK Incorporated.

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Year:  2015        PMID: 25856810     DOI: 10.3928/02793695-20150323-01

Source DB:  PubMed          Journal:  J Psychosoc Nurs Ment Health Serv        ISSN: 0279-3695            Impact factor:   1.098


  3 in total

Review 1.  Brexpiprazole: so far so good.

Authors:  Saibal Das; Preeti Barnwal; Blessed Winston A; Somnath Mondal; Indranil Saha
Journal:  Ther Adv Psychopharmacol       Date:  2016-02

Review 2.  Dopamine Receptor Partial Agonists for the Treatment of Bipolar Disorder.

Authors:  Jean-Michel Azorin; Nicolas Simon
Journal:  Drugs       Date:  2019-10       Impact factor: 9.546

Review 3.  Clinical role of brexpiprazole in depression and schizophrenia.

Authors:  Nishant B Parikh; Diana M Robinson; Anita H Clayton
Journal:  Ther Clin Risk Manag       Date:  2017-03-10       Impact factor: 2.423

  3 in total

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