Frank Vitinius1, Maria Ziemke, Wolfgang Albert. 1. aDepartment of Psychosomatics and Psychotherapy, University Hospital of Cologne, Cologne, Germany bDepartment of Psychosomatics, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13535 Berlin, Germany.
Abstract
PURPOSE OF REVIEW: Nonadherence is a major problem in heart transplantation (htx) and a challenge for clinical practice and research. In heart transplant recipients, nonadherence could cause chronic rejection of the transplanted heart followed by difficult clinical course and/or death of the patient. RECENT FINDINGS: Main topics are the relationship between psychological aspects and adherence, risk factors and prediction of nonadherence, strategies for improving adherence like single-dose immunosuppressant therapy and follow-up studies. SUMMARY: There is a lack of behavioral intervention studies. So-called targeted interventions should be defined for clinical practice and research with randomized controlled studies.
PURPOSE OF REVIEW: Nonadherence is a major problem in heart transplantation (htx) and a challenge for clinical practice and research. In heart transplant recipients, nonadherence could cause chronic rejection of the transplanted heart followed by difficult clinical course and/or death of the patient. RECENT FINDINGS: Main topics are the relationship between psychological aspects and adherence, risk factors and prediction of nonadherence, strategies for improving adherence like single-dose immunosuppressant therapy and follow-up studies. SUMMARY: There is a lack of behavioral intervention studies. So-called targeted interventions should be defined for clinical practice and research with randomized controlled studies.
Authors: Eulalia Roig; Sonia Mirabet; Mar Gomis-Pastor; Jan T De Pourcq; Irene Conejo; Anna Feliu; Vicens Brossa; Laura Lopez; Andreu Ferrero-Gregori; Anna Barata; M Antonia Mangues Journal: JMIR Mhealth Uhealth Date: 2020-02-04 Impact factor: 4.773