Literature DB >> 25854925

Limited experience, high body mass index and previous urethral surgery are risk factors for failure in open urethroplasty due to penile strictures.

Teresa O Ekerhult1, Klas Lindqvist1, Ralph Peeker1, Lars Grenabo1.   

Abstract

OBJECTIVE: The aim of this study was to evaluate outcomes and possible risk factors for failure of open urethroplasty due to penile urethral strictures.
MATERIALS AND METHODS: A retrospective chart review was undertaken of 90 patients with penile stricture undergoing 109 open urethroplasties between 2000 and 2011. In 80 urethroplasties, a one-stage procedure was performed: 68 of these had a pediculated penile skin flap, nine had a free buccal mucosal graft and three had a free skin graft. A two-stage procedure using buccal mucosa was performed in 29 urethroplasties. Failure was defined as when further urethral instrumentation was needed.
RESULTS: The mean age in the one-stage and two-stage groups were 50 and 54 years, respectively. The success rates in the corresponding groups were 65% and 72%, with follow-up times of 63 and 40 months, respectively. Multivariable analyses disclosed body mass index (BMI) and previous urethral surgery to be significant risk factors for failure in the one-stage group. Failure over time significantly decreased during the study period.
CONCLUSIONS: Both one- and two-stage penile urethroplasty demonstrated success rates in line with previous reports. Limited experience, high BMI and previous urethral surgery appear to be associated with less favourable outcome.

Entities:  

Keywords:  BMI; clinical experience; risk factors; urethral stricture; urethroplasty

Mesh:

Year:  2015        PMID: 25854925     DOI: 10.3109/21681805.2015.1030689

Source DB:  PubMed          Journal:  Scand J Urol        ISSN: 2168-1805            Impact factor:   1.612


  3 in total

Review 1.  Refractory Urethral Stricture Management: Indications for Alternative Grafts and Flaps.

Authors:  Alison C Levy; Alex J Vanni
Journal:  Curr Urol Rep       Date:  2018-02-26       Impact factor: 3.092

2.  Canadian Urological Association guideline on male urethral stricture.

Authors:  Keith F Rourke; Blayne Welk; Ron Kodama; Greg Bailly; Tim Davies; Nancy Santesso; Philippe D Violette
Journal:  Can Urol Assoc J       Date:  2020-10       Impact factor: 2.052

3.  Effect of body mass index on recurrence following urethroplasty.

Authors:  David E Rapp; James T Mills; Luriel I Smith-Harrison; Ryan P Smith; Raymond A Costabile
Journal:  Transl Androl Urol       Date:  2018-08
  3 in total

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