Literature DB >> 2585411

Acute, reversible hepatic failure associated with methotrexate treatment of rheumatoid arthritis.

D O Clegg1, D E Furst, K G Tolman, R Pogue.   

Abstract

We describe 2 patients who developed reversible decompensated liver disease while taking pulse dosed methotrexate (MTX) for rheumatoid arthritis. One of the patients was available for biopsy and had chronic active hepatitis--a lesion not previously described with MTX. This appears to be a unique and unusual manifestation of MTX hepatotoxicity.

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Year:  1989        PMID: 2585411

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  6 in total

1.  New directions in primary biliary cirrhosis.

Authors:  M C Bateson
Journal:  BMJ       Date:  1990-12-08

Review 2.  Ascites and other incidental findings revealing undiagnosed systemic rheumatoid arthritis.

Authors:  Matthew Chak Hin Szeto; Benjamin Disney; Philip Perkins; Gordon Wood
Journal:  BMJ Case Rep       Date:  2015-06-08

Review 3.  Clinical pharmacology and modification of autoimmunity and inflammation in rheumatoid disease.

Authors:  R Luqmani; C Gordon; P Bacon
Journal:  Drugs       Date:  1994-02       Impact factor: 9.546

Review 4.  Methotrexate in rheumatoid arthritis. An update.

Authors:  B Bannwarth; L Labat; Y Moride; T Schaeverbeke
Journal:  Drugs       Date:  1994-01       Impact factor: 9.546

5.  Fibrinous peritonitis in a patient with rheumatoid arthritis.

Authors:  R Kapoor; E Dean; T Palferman; Z Khan
Journal:  J R Soc Med       Date:  2005-04       Impact factor: 18.000

Review 6.  [Methotrexate therapy in rheumatologic diseases--an update].

Authors:  Edmund Cauza; Attila Dunky
Journal:  Wien Med Wochenschr       Date:  2003
  6 in total

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