| Literature DB >> 25853771 |
Jun Zheng1, Shao-Bo Wang1, Chao Zheng1, Shu-Li You1.
Abstract
A Rh-catalyzed enantioselective dearomatization of 1-aryl-2-naphthols with internal alkynes via C-H functionalization reaction was achieved. In the presence of a chiral Cp/Rh catalyst and combined oxidants of Cu(OAc)2 and air (oxygen), various highly enantioenriched spirocyclic enones bearing an all-carbon quaternary stereogenic center could be synthesized in 33-98% yields with up to 97:3 er.Entities:
Year: 2015 PMID： 25853771 DOI： 10.1021/jacs.5b01707
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419