Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Proteomics

Literature DB >> 25853048

Proteomics - The research frontier in periodontics.

Abhaya Gupta¹, Vivek Govila², Ashish Saini³.

Abstract

Periodontitis is an inflammatory condition resulting from the interplay between the infectious agents and host factors. Various protein molecules play a vital role in the initiation, progression and severity of periodontal diseases. The study of proteins as biomarkers in periodontal diseases has been highlighted during the last few years. In periodontitis multiple bacteria derived (e.g. collagen degrading enzymes, elastase like enzymes etc) and host derived mediators (eg. PGE2, TNF, IL1, IL6, MMP's etc) expressed in the saliva and gingival crevicular fluid, can be utilized as diagnostic markers for the disease. Another significant development regarding human genes and proteins has been the discovery of potential new drugs for the treatment of periodontal diseases. Therefore the information of the proteins involved in the pathogenesis of periodontal diseases can be utilized for its diagnosis, prevention and treatment.

Entities: Chemical Disease Gene Species

Keywords: Biomarkers; Genome; Periodontitis; Porphyromonas gingivalis; Proteome

Year: 2015 PMID： 25853048 PMCID： PMC4382510 DOI： 10.1016/j.jobcr.2015.01.001

Source DB: PubMed Journal: J Oral Biol Craniofac Res ISSN： 2212-4268

25 in total

Review 1. Are cementoblasts a subpopulation of osteoblasts or a unique phenotype?

Authors: D D Bosshardt
Journal: J Dent Res Date: 2005-05 Impact factor: 6.116

2. The role of gingival crevicular fluid and salivary interstitial collagenases in human periodontal diseases.

Authors: T Sorsa; K Suomalainen; V J Uitto
Journal: Arch Oral Biol Date: 1990 Impact factor: 2.633

3. From proteins to proteomes: large scale protein identification by two-dimensional electrophoresis and amino acid analysis.

Authors: M R Wilkins; C Pasquali; R D Appel; K Ou; O Golaz; J C Sanchez; J X Yan; A A Gooley; G Hughes; I Humphery-Smith; K L Williams; D F Hochstrasser
Journal: Biotechnology (N Y) Date: 1996-01

4. Alterations in the salivary proteome associated with periodontitis.

Authors: Brendan J Haigh; Kevin W Stewart; John R K Whelan; Matthew P G Barnett; Grant A Smolenski; Thomas T Wheeler
Journal: J Clin Periodontol Date: 2010-03 Impact factor: 8.728

Review 5. Mass spectrometry-based proteomics and its application to studies of Porphyromonas gingivalis invasion and pathogenicity.

Authors: Richard J Lamont; Marina Meila; Qiangwei Xia; Murray Hackett
Journal: Infect Disord Drug Targets Date: 2006-09

6. The ClpC ATPase of Listeria monocytogenes is a general stress protein required for virulence and promoting early bacterial escape from the phagosome of macrophages.

Authors: C Rouquette; C de Chastellier; S Nair; P Berche
Journal: Mol Microbiol Date: 1998-03 Impact factor: 3.501

7. Proteome analysis of Porphyromonas gingivalis cells placed in a subcutaneous chamber of mice.

Authors: M Yoshimura; N Ohara; Y Kondo; M Shoji; S Okano; Y Nakano; Y Abiko; K Nakayama
Journal: Oral Microbiol Immunol Date: 2008-10

8. Role of Fusobacterium nucleatum and coaggregation in anaerobe survival in planktonic and biofilm oral microbial communities during aeration.

Authors: D J Bradshaw; P D Marsh; G K Watson; C Allison
Journal: Infect Immun Date: 1998-10 Impact factor: 3.441

9. Bone remodeling biomarkers of periodontal disease in saliva.

Authors: Brandon D Frodge; Jeffrey L Ebersole; Richard J Kryscio; Mark V Thomas; Craig S Miller
Journal: J Periodontol Date: 2008-10 Impact factor: 6.993

10. Changes in the protein expression of yeast as a function of carbon source.

Authors: Ji Gao; Gregory J Opiteck; Mark S Friedrichs; Ashok R Dongre; Stanley A Hefta
Journal: J Proteome Res Date: 2003 Nov-Dec Impact factor: 4.466

10 in total

1. Neutrophil elastase aggravates periodontitis by disrupting gingival epithelial barrier via cleaving cell adhesion molecules.

Authors: Takumi Hiyoshi; Hisanori Domon; Tomoki Maekawa; Hikaru Tamura; Toshihito Isono; Satoru Hirayama; Karin Sasagawa; Fumio Takizawa; Koichi Tabeta; Yutaka Terao
Journal: Sci Rep Date: 2022-05-17 Impact factor: 4.996

2. The Treponema denticola FhbB Protein Is a Dominant Early Antigen That Elicits FhbB Variant-Specific Antibodies That Block Factor H Binding and Cleavage by Dentilisin.

Authors: Daniel P Miller; Lee D Oliver; Brittney K Tegels; Lucas A Reed; Nathaniel S O'Bier; Kurni Kurniyati; Lindsay A Faust; Christine K Lawson; Anna M Allard; Melissa J Caimano; Richard T Marconi
Journal: Infect Immun Date: 2016-06-23 Impact factor: 3.441

3. Analysis of protein expression in periodontal pocket tissue: a preliminary study.

Authors: Emanuela Monari; Aurora Cuoghi; Elisa Bellei; Stefania Bergamini; Andrea Lucchi; Aldo Tomasi; Pierpaolo Cortellini; Davide Zaffe; Carlo Bertoldi
Journal: Proteome Sci Date: 2015-12-30 Impact factor: 2.480

4. Identification of a discriminative metabolomic fingerprint of potential clinical relevance in saliva of patients with periodontitis using 1H nuclear magnetic resonance (NMR) spectroscopy.

Authors: Matthias Rzeznik; Mohamed Nawfal Triba; Pierre Levy; Sébastien Jungo; Eliot Botosoa; Boris Duchemann; Laurence Le Moyec; Jean-François Bernaudin; Philippe Savarin; Dominique Guez
Journal: PLoS One Date: 2017-08-24 Impact factor: 3.240

Review 5. Oral microbiome and peri-implant diseases: where are we now?

Authors: Rafał Pokrowiecki; Agnieszka Mielczarek; Tomasz Zaręba; Stefan Tyski
Journal: Ther Clin Risk Manag Date: 2017-11-29 Impact factor: 2.423

Review 6. Proteomics approach for biomarkers and diagnosis of periodontitis: systematic review.

Authors: Muhammad Ihsan Rizal; Yuniarti Soeroso; Benso Sulijaya; Bobby F Assiddiq; Endang W Bachtiar; Boy M Bachtiar
Journal: Heliyon Date: 2020-06-04

Review 7. The New Era of Salivaomics in Dentistry: Frontiers and Facts in the Early Diagnosis and Prevention of Oral Diseases and Cancer.

Authors: Flavia Papale; Simona Santonocito; Alessandro Polizzi; Antonino Lo Giudice; Saverio Capodiferro; Gianfranco Favia; Gaetano Isola
Journal: Metabolites Date: 2022-07-12