Literature DB >> 25850995

Conservative management of neurocysticercosis in a patient with hematopoietic stem cell transplantation: a case report and review.

S Purvey1, K Lu1, S K Mukkamalla1, P Anandi1, B Dumitriu1, S Kranick2, D A Hammoud3, E O'Connell4, A L Oh5, J Barrett1, S Mahanty4, M Battiwalla1.   

Abstract

Neurocysticercosis, an infection of the central nervous system with the larval stage of the cestode Taenia solium, is common in developing countries but its occurrence and management in allogeneic hematopoietic stem cell transplantation (HSCT) has not been reported previously, to our knowledge. We report the case of an immigrant female patient who underwent a matched-related allogeneic HSCT for acute lymphoblastic leukemia and was incidentally found to have a solitary viable neurocysticercosis lesion. However, despite severe immunosuppression, the size of the cyst did not increase. More importantly, restoration of the immune system did not induce significant inflammation or seizures. Subsequent follow-up demonstrated complete resolution of the neurocysticercosis lesion. Thus, in the setting of HSCT, an asymptomatic patient with a single neurocysticercosis lesion was successfully managed without the use of anthelmintics, steroids, or anti-epileptics.
© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Taenia solium; allogeneic hematopoietic stem cell transplantation; anthelmintics; neurocysticercosis; parasite; tapeworm

Mesh:

Year:  2015        PMID: 25850995      PMCID: PMC4464908          DOI: 10.1111/tid.12392

Source DB:  PubMed          Journal:  Transpl Infect Dis        ISSN: 1398-2273            Impact factor:   2.228


  50 in total

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Journal:  J Infect Dis       Date:  1989-01       Impact factor: 5.226

2.  Neurocysticercosis in children: clinical findings and response to albendazole therapy in a randomized, double-blind, placebo-controlled trial in newly diagnosed cases.

Authors:  Siddhartha Gogia; Bibek Talukdar; Veena Choudhury; Balvinder Singh Arora
Journal:  Trans R Soc Trop Med Hyg       Date:  2003 Jul-Aug       Impact factor: 2.184

3.  A trial of antiparasitic treatment to reduce the rate of seizures due to cerebral cysticercosis.

Authors:  Héctor H Garcia; E Javier Pretell; Robert H Gilman; S Manuel Martinez; Lawrence H Moulton; Oscar H Del Brutto; Genaro Herrera; Carlton A W Evans; Armando E Gonzalez
Journal:  N Engl J Med       Date:  2004-01-15       Impact factor: 91.245

Review 4.  Imaging findings in neurocysticercosis.

Authors:  Héctor H García; Oscar H Del Brutto
Journal:  Acta Trop       Date:  2003-06       Impact factor: 3.112

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Authors:  G Gordillo-Paniagua; R Muñoz-Arizpe; R Ponsa-Molina
Journal:  Nephron       Date:  1987       Impact factor: 2.847

6.  Prognostic factors for seizure recurrence after withdrawal of antiepileptic drugs in patients with neurocysticercosis.

Authors:  O H Del Brutto
Journal:  Neurology       Date:  1994-09       Impact factor: 9.910

7.  Clinical evaluation of the cysticercosis enzyme-linked immunoelectrotransfer blot in patients with neurocysticercosis.

Authors:  M Wilson; R T Bryan; J A Fried; D A Ware; P M Schantz; J B Pilcher; V C Tsang
Journal:  J Infect Dis       Date:  1991-11       Impact factor: 5.226

8.  Epilepsy due to neurocysticercosis: analysis of 203 patients.

Authors:  O H Del Brutto; R Santibañez; C A Noboa; R Aguirre; E Díaz; T A Alarcón
Journal:  Neurology       Date:  1992-02       Impact factor: 9.910

Review 9.  Relationship between epilepsy and tropical diseases. Commission on Tropical Diseases of the International League Against Epilepsy.

Authors: 
Journal:  Epilepsia       Date:  1994 Jan-Feb       Impact factor: 5.864

10.  Seizure outcome in patients with a solitary cerebral cysticercus granuloma.

Authors:  Vedantam Rajshekhar; Lakshmanan Jeyaseelan
Journal:  Neurology       Date:  2004-06-22       Impact factor: 9.910

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  2 in total

1.  Cerebellar Neurocysticercosis as Long-Term Complication of Allogeneic Haematopoietic Stem Cell Transplantation from Haploidentical Donor.

Authors:  Federico Meconi; Giulia Ciangola; Benedetta Mariotti; Raffaella Cerretti; Laura Cudillo; William Arcese; Alessandra Picardi
Journal:  Case Rep Infect Dis       Date:  2019-09-19

2.  Dexamethasone-loaded zeolitic imidazolate frameworks nanocomposite hydrogel with antibacterial and anti-inflammatory effects for periodontitis treatment.

Authors:  Ning Li; Lianyan Xie; Yicheng Wu; Yan Wu; Yongjia Liu; Yiming Gao; Jie Yang; Xiuyin Zhang; Liting Jiang
Journal:  Mater Today Bio       Date:  2022-07-20
  2 in total

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