| Literature DB >> 2585035 |
A Zaniboni1, E Simoncini, P Marpicati, E Montini, V Ferrari, G Marini.
Abstract
Fourteen patients with metastatic renal cell carcinoma (RCC) were treated with high-dose folinic acid (HDFA): 200 mg/m2 i.v. and 5-fluorouracil (5-FU): 370 mg/m2 i.v. for 5 consecutive days every 28 days. Severe oral mucositis (WHO grade III-IV) was experienced by two patients, whereas hematological toxicity was mild. No complete or partial remission was observed. Short-lasting stable disease occurred in 8 patients (median = 5 months, range 2-11). This combination does not need further evaluation in patients with RCC.Entities:
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Year: 1989 PMID： 2585035 DOI： 10.1080/1120009x.1989.11738921
Source DB: PubMed Journal: J Chemother ISSN： 1120-009X Impact factor: 1.714