Literature DB >> 25849920

The zDHHC family of S-acyltransferases.

Kimon Lemonidis1, Martin W Werno1, Jennifer Greaves1, Cinta Diez-Ardanuy1, Maria C Sanchez-Perez1, Christine Salaun1, David M Thomson1, Luke H Chamberlain1.   

Abstract

The discovery of the zDHHC family of S-acyltransferase enzymes has been one of the major breakthroughs in the S-acylation field. Now, more than a decade since their discovery, major questions centre on profiling the substrates of individual zDHHC enzymes (there are 24 ZDHHC genes and several hundred S-acylated proteins), defining the mechanisms of enzyme-substrate specificity and unravelling the importance of this enzyme family for cellular physiology and pathology.

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Year:  2015        PMID： 25849920     DOI： 10.1042/BST20140270

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  21 in total

1.  Fatty Acid Synthase Promotes the Palmitoylation of Chikungunya Virus nsP1.

Authors:  Na Zhang; Hongjian Zhao; Leiliang Zhang
Journal:  J Virol       Date:  2019-01-17       Impact factor: 5.103

2.  Protein palmitoylation: Palmitoyltransferases and their specificity.

Authors:  Sabina Tabaczar; Aleksander Czogalla; Joanna Podkalicka; Agnieszka Biernatowska; Aleksander F Sikorski
Journal:  Exp Biol Med (Maywood)       Date:  2017-05-09

Review 3.  Protein depalmitoylases.

Authors:  Sang Joon Won; Melanie Cheung See Kit; Brent R Martin
Journal:  Crit Rev Biochem Mol Biol       Date:  2017-12-14       Impact factor: 8.250

4.  Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.

Authors:  Erica L Gorenberg; Sofia Massaro Tieze; Betül Yücel; Helen R Zhao; Vicky Chou; Gregory S Wirak; Susumu Tomita; TuKiet T Lam; Sreeganga S Chandra
Journal:  PLoS Biol       Date:  2022-03-31       Impact factor: 8.029

Review 5.  CaMKII regulates the depalmitoylation and synaptic removal of the scaffold protein AKAP79/150 to mediate structural long-term depression.

Authors:  Kevin M Woolfrey; Heather O'Leary; Dayton J Goodell; Holly R Robertson; Eric A Horne; Steven J Coultrap; Mark L Dell'Acqua; K Ulrich Bayer
Journal:  J Biol Chem       Date:  2017-12-01       Impact factor: 5.157

Review 6.  Protein Lipidation in Cell Signaling and Diseases: Function, Regulation, and Therapeutic Opportunities.

Authors:  Baoen Chen; Yang Sun; Jixiao Niu; Gopala K Jarugumilli; Xu Wu
Journal:  Cell Chem Biol       Date:  2018-05-31       Impact factor: 8.116

7.  S-Acylation of Proteins of Coronavirus and Influenza Virus: Conservation of Acylation Sites in Animal Viruses and DHHC Acyltransferases in Their Animal Reservoirs.

Authors:  Dina A Abdulrahman; Xiaorong Meng; Michael Veit
Journal:  Pathogens       Date:  2021-05-29

Review 8.  Palmitoylation: a protein S-acylation with implications for breast cancer.

Authors:  Alison M Anderson; Mark A Ragan
Journal:  NPJ Breast Cancer       Date:  2016-10-19

9.  Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome.

Authors:  Richard S Beard; Xiaoyuan Yang; Jamie E Meegan; Jonathan W Overstreet; Clement G Y Yang; John A Elliott; Jason J Reynolds; Byeong J Cha; Christopher D Pivetti; David A Mitchell; Mack H Wu; Robert J Deschenes; Sarah Y Yuan
Journal:  Nat Commun       Date:  2016-09-22       Impact factor: 14.919

10.  Biological processes and signal transduction pathways regulated by the protein methyltransferase SETD7 and their significance in cancer.

Authors:  Inês de Albuquerque Almeida Batista; Luisa Alejandra Helguero
Journal:  Signal Transduct Target Ther       Date:  2018-07-13
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