Literature DB >> 25849270

Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs?

Claes B Wollheim1, Pierre Maechler1.   

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Year:  2015        PMID： 25849270     DOI： 10.1038/nm.3835

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  12 in total

1.  Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells.

Authors:  Nicole Feldmann; Rafael Martin del Rio; Asllan Gjinovci; Jorge Tamarit-Rodriguez; Claes B Wollheim; Andreas Wiederkehr
Journal:  Mol Cell Endocrinol       Date:  2011-03-01       Impact factor: 4.102

2.  Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

Authors:  P Maechler; C B Wollheim
Journal:  Nature       Date:  1999-12-09       Impact factor: 49.962

3.  Calcineurin signaling regulates human islet {beta}-cell survival.

Authors:  Scott A Soleimanpour; Michael F Crutchlow; Alana M Ferrari; Jeffrey C Raum; David N Groff; Matthew M Rankin; Chengyang Liu; Diva D De León; Ali Naji; Jake A Kushner; Doris A Stoffers
Journal:  J Biol Chem       Date:  2010-10-13       Impact factor: 5.157

4.  Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators.

Authors:  Matilde Colella; Francesca Grisan; Valerie Robert; Jay D Turner; Andrew P Thomas; Tullio Pozzan
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-19       Impact factor: 11.205

5.  Expression and role of ionotropic glutamate receptors in pancreatic islet cells.

Authors:  N Inagaki; H Kuromi; T Gonoi; Y Okamoto; H Ishida; Y Seino; T Kaneko; T Iwanaga; S Seino
Journal:  FASEB J       Date:  1995-05       Impact factor: 5.191

6.  Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance.

Authors:  Prasanna K Dadi; Nicholas C Vierra; Alessandro Ustione; David W Piston; Roger J Colbran; David A Jacobson
Journal:  J Biol Chem       Date:  2014-03-13       Impact factor: 5.157

7.  Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.

Authors:  Jan Marquard; Silke Otter; Alena Welters; Alin Stirban; Annelie Fischer; Jan Eglinger; Diran Herebian; Olaf Kletke; Maša Skelin Klemen; Andraž Stožer; Stephan Wnendt; Lorenzo Piemonti; Martin Köhler; Jorge Ferrer; Bernard Thorens; Freimut Schliess; Marjan Slak Rupnik; Tim Heise; Per-Olof Berggren; Nikolaj Klöcker; Thomas Meissner; Ertan Mayatepek; Daniel Eberhard; Martin Kragl; Eckhard Lammert
Journal:  Nat Med       Date:  2015-03-16       Impact factor: 53.440

8.  Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.

Authors:  Laurène Vetterli; Stefania Carobbio; Shirin Pournourmohammadi; Rafael Martin-Del-Rio; Dorte M Skytt; Helle S Waagepetersen; Jorge Tamarit-Rodriguez; Pierre Maechler
Journal:  Mol Biol Cell       Date:  2012-08-08       Impact factor: 4.138

9.  Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.

Authors:  Ghupurjan Gheni; Masahito Ogura; Masahiro Iwasaki; Norihide Yokoi; Kohtaro Minami; Yasumune Nakayama; Kazuo Harada; Benoit Hastoy; Xichen Wu; Harumi Takahashi; Kazushi Kimura; Toshiya Matsubara; Ritsuko Hoshikawa; Naoya Hatano; Kenji Sugawara; Tadao Shibasaki; Nobuya Inagaki; Takeshi Bamba; Akira Mizoguchi; Eiichiro Fukusaki; Patrik Rorsman; Susumu Seino
Journal:  Cell Rep       Date:  2014-10-16       Impact factor: 9.423

Review 10.  β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.

Authors:  Philippe A Halban; Kenneth S Polonsky; Donald W Bowden; Meredith A Hawkins; Charlotte Ling; Kieren J Mather; Alvin C Powers; Christopher J Rhodes; Lori Sussel; Gordon C Weir
Journal:  Diabetes Care       Date:  2014-05-08       Impact factor: 19.112
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  8 in total

1.  Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer's Disease.

Authors:  Miren Ettcheto; Elena Sánchez-López; Yaiza Gómez-Mínguez; Henrry Cabrera; Oriol Busquets; Carlos Beas-Zarate; Maria Luisa García; Eva Carro; Gemma Casadesus; Carme Auladell; Manuel Vázquez Carrera; Jaume Folch; Antoni Camins
Journal:  Mol Neurobiol       Date:  2018-02-05       Impact factor: 5.590

Review 2.  Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and Analysis.

Authors:  Jurij Dolenšek; Denis Špelič; Maša Skelin Klemen; Borut Žalik; Marko Gosak; Marjan Slak Rupnik; Andraž Stožer
Journal:  Sensors (Basel)       Date:  2015-10-28       Impact factor: 3.576

Review 3.  Memantine for the Treatment of Dementia: A Review on its Current and Future Applications.

Authors:  Jaume Folch; Oriol Busquets; Miren Ettcheto; Elena Sánchez-López; Ruben Dario Castro-Torres; Ester Verdaguer; Maria Luisa Garcia; Jordi Olloquequi; Gemma Casadesús; Carlos Beas-Zarate; Carme Pelegri; Jordi Vilaplana; Carme Auladell; Antoni Camins
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

4.  AMPK Profiling in Rodent and Human Pancreatic Beta-Cells under Nutrient-Rich Metabolic Stress.

Authors:  Thierry Brun; Cecilia Jiménez-Sánchez; Jesper Grud Skat Madsen; Noushin Hadadi; Dominique Duhamel; Clarissa Bartley; Lucie Oberhauser; Mirko Trajkovski; Susanne Mandrup; Pierre Maechler
Journal:  Int J Mol Sci       Date:  2020-06-01       Impact factor: 5.923

Review 5.  Glutamate as intracellular and extracellular signals in pancreatic islet functions.

Authors:  Harumi Takahashi; Norihide Yokoi; Susumu Seino
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2019       Impact factor: 3.493

6.  The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging.

Authors:  Myriam Abarkan; Julien Gaitan; Fanny Lebreton; Romain Perrier; Manon Jaffredo; Christophe Mulle; Christophe Magnan; Matthieu Raoux; Jochen Lang
Journal:  Mol Metab       Date:  2019-10-01       Impact factor: 7.422

7.  Effects of dextromethorphan as add-on to sitagliptin on blood glucose and serum insulin concentrations in individuals with type 2 diabetes mellitus: a randomized, placebo-controlled, double-blinded, multiple crossover, single-dose clinical trial.

Authors:  J Marquard; A Stirban; F Schliess; F Sievers; A Welters; S Otter; A Fischer; S Wnendt; T Meissner; T Heise; E Lammert
Journal:  Diabetes Obes Metab       Date:  2015-10-26       Impact factor: 6.577

8.  Memantine has no effect on KATP channels in pancreatic β cells.

Authors:  Ryota Imai; Shingen Misaka; Shoichiro Horita; Shoko Yokota; Rie O'hashi; Yuko Maejima; Kenju Shimomura
Journal:  BMC Res Notes       Date:  2018-08-25
  8 in total

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