Literature DB >> 25849269

Harnessing gene repression to inhibit leukemia.

Peter J Harte1, Patricia Ernst2.   

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Year:  2015        PMID： 25849269     DOI： 10.1038/nm.3834

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  9 in total

1.  The diversity of histone versus nonhistone sirtuin substrates.

Authors:  Paloma Martínez-Redondo; Alejandro Vaquero
Journal:  Genes Cancer       Date:  2013-03

Review 2.  Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.

Authors:  Bin E Li; Patricia Ernst
Journal:  Exp Hematol       Date:  2014-09-28       Impact factor: 3.084

3.  Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.

Authors:  Scott R Daigle; Edward J Olhava; Carly A Therkelsen; Aravind Basavapathruni; Lei Jin; P Ann Boriack-Sjodin; Christina J Allain; Christine R Klaus; Alejandra Raimondi; Margaret Porter Scott; Nigel J Waters; Richard Chesworth; Mikel P Moyer; Robert A Copeland; Victoria M Richon; Roy M Pollock
Journal:  Blood       Date:  2013-06-25       Impact factor: 22.113

4.  SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation.

Authors:  Alejandro Vaquero; Michael Scher; Hediye Erdjument-Bromage; Paul Tempst; Lourdes Serrano; Danny Reinberg
Journal:  Nature       Date:  2007-11-15       Impact factor: 49.962

Review 5.  The Sir2 family of protein deacetylases.

Authors:  Gil Blander; Leonard Guarente
Journal:  Annu Rev Biochem       Date:  2004       Impact factor: 23.643

6.  Dot1p modulates silencing in yeast by methylation of the nucleosome core.

Authors:  Fred van Leeuwen; Philip R Gafken; Daniel E Gottschling
Journal:  Cell       Date:  2002-06-14       Impact factor: 41.582

7.  DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.

Authors:  Chun-Wei Chen; Richard P Koche; Amit U Sinha; Aniruddha J Deshpande; Nan Zhu; Rowena Eng; John G Doench; Haiming Xu; Scott H Chu; Jun Qi; Xi Wang; Christopher Delaney; Kathrin M Bernt; David E Root; William C Hahn; James E Bradner; Scott A Armstrong
Journal:  Nat Med       Date:  2015-03-30       Impact factor: 53.440

8.  Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance.

Authors:  Satyendra K Singh; Carrie A Williams; Kimberly Klarmann; Sandra S Burkett; Jonathan R Keller; Philipp Oberdoerffer
Journal:  J Exp Med       Date:  2013-04-29       Impact factor: 14.307

9.  The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis.

Authors:  Bibhu P Mishra; Kristin M Zaffuto; Erika L Artinger; Tonis Org; Hanna K A Mikkola; Chao Cheng; Malek Djabali; Patricia Ernst
Journal:  Cell Rep       Date:  2014-05-09       Impact factor: 9.423
  9 in total

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