| Literature DB >> 25849154 |
Chong Shen1, Ren-Rong Liu1, Ren-Jie Fan1, Ying-Long Li1, Teng-Fei Xu1, Jian-Rong Gao1, Yi-Xia Jia1.
Abstract
A highly enantioselective intramolecular arylative dearomatization of indoles via palladium-catalyzed reductive Heck reactions was developed. The new strategy led to a series of optically active indolines bearing C2-quaternary stereocenters in modest to good yields with excellent enantioselectivities (up to 99% ee).Entities:
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Year: 2015 PMID： 25849154 DOI： 10.1021/jacs.5b01705
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419