Literature DB >> 25847636

Quality-adjusted cost of care: a meaningful way to measure growth in innovation cost versus the value of health gains.

Darius Lakdawalla1, Jason Shafrin2, Claudio Lucarelli3, Sean Nicholson4, Zeba M Khan5, Tomas J Philipson6.   

Abstract

Technology drives both health care spending and health improvement. Yet policy makers rarely see measures of cost growth that account for both effects. To fill this gap, we present the quality-adjusted cost of care, which illustrates cost growth net of growth in the value of health improvements, measured as survival gains multiplied by the value of survival. We applied the quality-adjusted cost of care to two cases. For colorectal cancer, drug cost per patient increased by $34,493 between 1998 and 2005 as a result of new drug launches, but value from offsetting health improvements netted a modest $1,377 increase in quality-adjusted cost of care. For multiple myeloma, new therapies increased treatment cost by $72,937 between 2004 and 2009, but offsetting health benefits lowered overall quality-adjusted cost of care by $67,863. However, patients with multiple myeloma on established first-line therapies saw costs rise without corresponding benefits. All three examples document rapid cost growth, but they provide starkly different answers to the question of whether society got what it paid for. Project HOPE—The People-to-People Health Foundation, Inc.

Entities:  

Keywords:  Cost of Health Care; Health Economics; Health Spending

Mesh:

Year:  2015        PMID: 25847636      PMCID: PMC4406284          DOI: 10.1377/hlthaff.2014.0639

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  7 in total

1.  The Willingness to Pay for a Quality Adjusted Life Year: A Review of the Empirical Literature.

Authors:  Linda Ryen; Mikael Svensson
Journal:  Health Econ       Date:  2014-07-28       Impact factor: 3.046

2.  A 1-year double-blind study of 2 doses of long-acting risperidone in stable patients with schizophrenia or schizoaffective disorder.

Authors:  George M Simpson; Ramy A Mahmoud; Robert A Lasser; Mary Kujawa; Cynthia A Bossie; Ibrahim Turkoz; Steven Rodriguez; Georges M Gharabawi
Journal:  J Clin Psychiatry       Date:  2006-08       Impact factor: 4.384

3.  Total cost comparison in relapsed/refractory multiple myeloma.

Authors:  Brian Durie; Gary Binder; Chris Pashos; Zeba Khan; Mohamad Hussein; Ivan Borrello
Journal:  J Med Econ       Date:  2013-03-19       Impact factor: 2.448

4.  Cost of care for elderly cancer patients in the United States.

Authors:  K Robin Yabroff; Elizabeth B Lamont; Angela Mariotto; Joan L Warren; Marie Topor; Angela Meekins; Martin L Brown
Journal:  J Natl Cancer Inst       Date:  2008-04-29       Impact factor: 13.506

Review 5.  Multiple myeloma.

Authors:  Marc S Raab; Klaus Podar; Iris Breitkreutz; Paul G Richardson; Kenneth C Anderson
Journal:  Lancet       Date:  2009-06-21       Impact factor: 79.321

6.  Lenalidomide for multiple myeloma: cost-effectiveness in patients with one prior therapy in England and Wales.

Authors:  Ruth E Brown; Sean Stern; Sujith Dhanasiri; Steve Schey
Journal:  Eur J Health Econ       Date:  2012-05-10

7.  Early versus delayed autologous stem cell transplant in patients receiving novel therapies for multiple myeloma.

Authors:  Neil C Dunavin; Lai Wei; Patrick Elder; Gary S Phillips; Don M Benson; Craig C Hofmeister; Sam Penza; Carli Greenfield; Karen S Rose; Gisele Rieser; Lisa Merritt; Jill Ketcham; Nyla Heerema; John C Byrd; Steven M Devine; Yvonne A Efebera
Journal:  Leuk Lymphoma       Date:  2012-12-31
  7 in total
  7 in total

1.  Chemotherapy Use in the Months Before Death and Estimated Costs of Care in the Last Week of Life.

Authors:  Melissa M Garrido; Holly G Prigerson; Yuhua Bao; Paul K Maciejewski
Journal:  J Pain Symptom Manage       Date:  2016-02-17       Impact factor: 3.612

2.  A Satellite Account for Health in the United States.

Authors:  David M Cutler; Kaushik Ghosh; Kassandra L Messer; Trivellore Raghunathan; Allison B Rosen; Susan T Stewart
Journal:  Am Econ Rev       Date:  2022-02

Review 3.  Assessment of cost of innovation versus the value of health gains associated with treatment of chronic hepatitis C in the United States: The quality-adjusted cost of care.

Authors:  Zobair M Younossi; Haesuk Park; Douglas Dieterich; Sammy Saab; Aijaz Ahmed; Stuart C Gordon
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

4.  Challenging Perceptions About Oncology Product Pricing in Breast and Colorectal Cancer.

Authors:  Anthony Barron; Tim Wilsdon
Journal:  Pharmaceut Med       Date:  2016-11-10

5.  Assessing Variation in the Cost of Palivizumab for Respiratory Syncytial Virus Prevention in Preterm Infants.

Authors:  Ahva Shahabi; Desi Peneva; Devin Incerti; Kimmie McLaurin; Warren Stevens
Journal:  Pharmacoecon Open       Date:  2018-03

6.  Temporal Trends in Survival and Healthcare Costs in Patients with Multiple Myeloma in the United States.

Authors:  Eric M Maiese; Kristin A Evans; Bong-Chul Chu; Debra E Irwin
Journal:  Am Health Drug Benefits       Date:  2018-02

7.  The value of survival gains from therapeutic innovations for US patients with relapsed/refractory multiple myeloma.

Authors:  Joanna P MacEwan; Istvan Majer; Jacquelyn W Chou; Sumeet Panjabi
Journal:  Ther Adv Hematol       Date:  2021-07-03
  7 in total

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